1 Result for "

ML141

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ML141" in MCE Product Catalog:

35
35 Cited Publications
Cat. No.: HY-12755
CAS No.: 71203-35-5
Purity:  99.96%
Synonyms: CID-2950007
Target:  

Ras Apoptosis

Research Areas:  

Cancer

ML141 (CID-2950007) is a potent, allosteric, selective and reversible non-competitive inhibitor of Cdc42 GTPase. ML141 inhibits Cdc42 wild type and Cdc42 Q61L mutant with EC50s of 2.1 and 2.6 μM, respectively. ML141 shows low micromolar potency and selectivity against other members of the Rho family of GTPases (Rac1, Rab2, Rab7). ML141 do not show cytotoxicity in multiple cell lines .
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