1 Result for "

ML216

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ML216" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-12342
CAS No.: 1430213-30-1
Purity:  99.89%
Synonyms: CID-49852229
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

ML216 (CID-49852229) is a potent, selective and cell permeable inhibitor of the DNA unwinding activity of BLM helicase with IC50s of 2.98 μM and 0.97 μM for BLM full-length and BLM 636-1298, respectively. ML216 inhibits ssDNA-dependent ATPase activity of BLM with a Ki of 1.76 μM. Antitumor avtivity .
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