1 Result for "

ML246

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ML246" in MCE Product Catalog:

Cat. No.: HY-120118
CAS No.: 1443414-10-5
Purity:  99.90%
Synonyms: ML246
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Metarrestin (ML246) is an orally active, first-in-class and specific perinucleolar compartment inhibitor. Metarrestin disrupts the nucleolar structure and inhibits RNA polymerase (Pol) I transcription, at least in part by interacting with the translation elongation factor eEF1A2. Metarrestin blocks metastatic development and extends survival in mouse cancer models .
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