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Pathways Recommended: MAPK/ERK Pathway
Results for "

MSTN pathway

" in MedChemExpress (MCE) Product Catalog:
Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-183504
    ActRIIB-IN-3

    		TGF-β Receptor Cancer
    ActRIIB-IN-3 is a ActRIIB inhibitor. ActRIIB-IN-3 inhibits the ActRIIB protein in the MSTN pathway and induces the reversal of skeletal muscle atrophy associated with cancer cachexia. ActRIIB-IN-3 is applicable for the research of cancer cachexia .
    ActRIIB-IN-3
  • HY-183005
    ActRIIB-IN-1

    		TGF-β Receptor Inflammation/Immunology Cancer
    ActRIIB-IN-1, 7-azaindole compound is an orally active activin type II receptor B (ActRIIB) inhibitor with an IC50 of 1.8 nM. ActRIIB-IN-1 can alleviate weight loss, muscle atrophy and decreased muscle strength caused by tumor cachexia, as well as improve appetite. ActRIIB-IN-1 can be used for the research of cancer cachexia .
    ActRIIB-IN-1

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