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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
Mucopolysaccharidosis IIIA
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "Mucopolysaccharidosis IIIA" in MCE Product Catalog:
Cat. No.: HY-D1632
CAS No.: 460085-45-4
Target:
Research Areas:
4-MU-α-GlcNS sodium is a fluorogenic substrate for heparan sulfate sulfamidase, with apparent Km values of 4 mM and 8 mM for fibroblast and leukocyte enzymes, respectively. 4-MU-α-GlcNS sodium undergoes enzymatic desulfation to generate an intermediate, which requires a second incubation with yeast α-glucosidase to hydrolyze and release 4-methylumbelliferone, detected by fluorescence at Ex/Em = 365/450 nm. 4-MU-α-GlcNS sodium is suitable for fibroblast homogenates, leukocytes, and dried leukocyte filter paper samples, and can be used for the detection and study of enzyme activity in mucopolysaccharidosis type IIIA .
Cat. No.: HY-P71307
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SGSH; Sulfoglucosamine Sulfamidase; N-Sulfoglucosamine Sulfohydrolase; Sulphamidase; HSS; N-Sulphoglucosamine Sulphohydrolase; MPS3A; Heparan Sulfate Sulfatase; SFMD; Sulfamidase; Mucopolysaccharidosis Type IIIA
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
