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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
N-WASP
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "N-WASP" in MCE Product Catalog:
2
2 Cited Publications
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Wiskostatin is a potent and selective inhibitor of neuronal Wiskott-Aldrich syndrome protein (N-WASP)-mediated actin polymerization by stabilization of the closed, autoinhibited conformation, thereby preventing Arp2/3 complex activation. Wiskostatin is also a dynamin inhibitor with an IC50 value of 20.7 μM and a potent inhibitor of clathrin-mediated endocytosis with an IC50 value of 6.9 μM. Wiskostatin causes a rapid, profound, and irreversible decrease in cellular ATP levels. Wiskostatin also induces disassembly of podosomes in a murine monocyte cell line .
1
1 Cited Publications
Cat. No.: HY-P1045
CAS No.: 380488-27-7
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Cat. No.: HY-P1045A
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Cat. No.: HY-RS15747
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WASL Human Pre-designed siRNA Set A contains three designed siRNAs for WASL gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-181446
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PtdIns-(4,5)-P2 (1,2-dipalmitoyl) ammonium (PI(4,5)P2) is a signaling molecule. PtdIns-(4,5)-P2 (1,2-dipalmitoyl) ammonium is critical at multiple stages of endocytosis, where it sequentially recruits adaptor proteins and accessory proteins to endocytic sites. PtdIns-(4,5)-P2 (1,2-dipalmitoyl) ammonium is considered essential for maintaining the structure of the Golgi apparatus and the transport of proteins within the Golgi apparatus .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
