1 Result for "

NBT human myoblasts

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NBT human myoblasts" in MCE Product Catalog:

Cat. No.: HY-158740
CAS No.: 2644636-20-2
Target:  

Ferroptosis

Research Areas:  

Neurological Disease

1(R)-(Trifluoromethyl)oleyl alcohol (compound (R)-24) is a trifluoromethyl alcohol derivative of Oleic acid (HY-N1446) with activity in multiple models of Friedreich ataxia (FRDA). 1(R)-(Trifluoromethyl)oleyl alcohol inhibits ferroptosis induced by Erastin (HY-15763) and decreases lipid peroxidation in NBT human myoblasts with frataxin (FXN) siRNA knockdown. 1(R)-(Trifluoromethyl)oleyl alcohol at 40 μM increases survival to 95% in a model of FRDA where a significant percentage of cell death is caused by FAC (HY-B1645) and BSO (HY-106376) .
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