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1(R)-(Trifluoromethyl)oleyl alcohol

1(R)-(Trifluoromethyl)oleyl alcohol (compound (R)-24) is a trifluoromethyl alcohol derivative of Oleic acid (HY-N1446) with activity in multiple models of Friedreich ataxia (FRDA). 1(R)-(Trifluoromethyl)oleyl alcohol inhibits ferroptosis induced by Erastin (HY-15763) and decreases lipid peroxidation in NBT human myoblasts with frataxin (FXN) siRNA knockdown. 1(R)-(Trifluoromethyl)oleyl alcohol at 40 μM increases survival to 95% in a model of FRDA where a significant percentage of cell death is caused by FAC (HY-B1645) and BSO (HY-106376).

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  • CAS No.: 2644636-20-2
  • Formula: C19H35F3O
  • Molecular Weight:336.48
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • 1(R)-(Trifluoromethyl)oleyl alcohol Chemical Structure
    1(R)-(Trifluoromethyl)oleyl alcohol Chemical Structure
CAS No.: 2644636-20-2
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  • 1(R)-(Trifluoromethyl)oleyl alcohol Chemical Structure
    1(R)-(Trifluoromethyl)oleyl alcohol Chemical Structure
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  • 1(R)-(Trifluoromethyl)oleyl alcohol