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Results for "

NREM

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-103181
    N6-Cyclopentyladenosine

    CPA; UK-80882

    		 Adenosine Receptor Apoptosis Cardiovascular Disease Neurological Disease Cancer
    N6-Cyclopentyladenosine (CPA) is a selective Adenosine A1 receptor agonist, with Ki values of 2.3 nM, 790 nM and 43 nM for human A1, A2A and A3 receptors, respectively. N6-cyclopentyladenosine increases Apoptosis. N6-Cyclopentyladenosine has antitumor activity against leukemia. N6-cyclopentyladenosine improves 5-fluorouracil (HY-90006)-induced hematopoietic damage, regulates sleep, and delays Aminophylline-induced clonic epileptic seizures .
    N6-Cyclopentyladenosine
  • HY-10896
    JNJ-10397049
    1 Publications Verification

    		 Orexin Receptor (OX Receptor) Neurological Disease
    JNJ-10397049 is a potent and selective orexin 2 receptor (OX2R) antagonist, with a pKi of 8.3. JNJ-10397049 is 600-fold selective for the OX2R over the OX1R .
    JNJ-10397049
  • HY-108015
    RO5263397

    		Trace Amine-associated Receptor (TAAR) Neurological Disease
    RO5263397 is a potent, selective, and orally available TAAR1 agonist, with EC50s of 17 and 35 nM for human TAAR1 and rat TAAR1, respectively. RO5263397 regulates wakefulness and EEG spectral composition. Antidepressant-like effect .
    RO5263397
  • HY-136922
    Orexin receptor antagonist 2

    		Orexin Receptor (OX Receptor) Neurological Disease
    Orexin receptor antagonist 2 (compound 30) is a potent orexin receptor antagonist with pKis of 7.69 and 9.78. Orexin receptor antagonist 2 has the potential for the research of insomnia .
    Orexin receptor antagonist 2
  • HY-12392R
    Iprindole (Standard)

    		Reference Standards Opioid Receptor Neurological Disease
    Iprindole (Standard) is the analytical standard of Iprindole. This product is intended for research and analytical applications. Iprindole, an opioid receptor agonist, is a tricyclic antidepressant. Iprindole shortens the immobility time in mice forced swimming test, which can be reversed by the opiate antagonist Naloxone (HY-17417A). Iprindole induces lamellar body formation but devoid of lamellar bodies. Iprindole hydrochloride can be used for the research of depression .
    Iprindole (Standard)
  • HY-10896R
    JNJ-10397049 (Standard)

    		Reference Standards Orexin Receptor (OX Receptor) Neurological Disease
    JNJ-10397049 (Standard) is the analytical standard of JNJ-10397049 (HY-10896). This product is intended for research and analytical applications. JNJ-10397049 is a potent and selective orexin 2 receptor (OX2R) antagonist, with a pKi of 8.3. JNJ-10397049 is 600-fold selective for the OX2R over the OX1R .
    JNJ-10397049 (Standard)
  • HY-115304
    UCM 793

    		Melatonin Receptor Neurological Disease
    UCM 793 is a non-selective MT1/MT2 receptor agonist (pKis: 9.09 (MT1 receptor); 9.19 (MT2 receptor)). UCM793 increases the number of episodes and decreases the length of the episodes of wakefulness. UCM 793 influences quality of the vigilance states. UCM 793 decreases sleep onset without having an effect on NREM sleep maintenance .
    UCM 793
  • HY-103181R
    N6-Cyclopentyladenosine (Standard)

    CPA (Standard); UK-80882 (Standard)

    		 Reference Standards Adenosine Receptor Apoptosis Cardiovascular Disease Neurological Disease Cancer
    N6-Cyclopentyladenosine (Standard) is the analytical standard of N6-Cyclopentyladenosine (HY-103181). This product is intended for research and analytical applications. N6-Cyclopentyladenosine (CPA) is a selective Adenosine A1 receptor agonist, with Ki values of 2.3 nM, 790 nM and 43 nM for human A1, A2A and A3 receptors, respectively. N6-cyclopentyladenosine increases Apoptosis. N6-Cyclopentyladenosine has antitumor activity against leukemia. N6-cyclopentyladenosine improves 5-fluorouracil (HY-90006)-induced hematopoietic damage, regulates sleep, and delays Aminophylline-induced clonic epileptic seizures .
    N6-Cyclopentyladenosine (Standard)
  • HY-108015R
    RO5263397 (Standard)

    		Reference Standards Trace Amine-associated Receptor (TAAR) Neurological Disease
    RO5263397 (Standard) is the analytical standard of RO5263397 (HY-108015). This product is intended for research and analytical applications. RO5263397 is a potent, selective, and orally available TAAR1 agonist, with EC50s of 17 and 35 nM for human TAAR1 and rat TAAR1, respectively. RO5263397 regulates wakefulness and EEG spectral composition. Antidepressant-like effect .
    RO5263397 (Standard)
  • HY-12392A
    Iprindole hydrochloride

    		Opioid Receptor Neurological Disease
    Iprindole hydrochloride, an opioid receptor agonist, is a tricyclic antidepressant. Iprindole hydrochloride shortens the immobility time in mice forced swimming test, which can be reversed by the opiate antagonist Naloxone (HY-17417A). Iprindole hydrochloride induces lamellar body formation but devoid of lamellar bodies. Iprindole hydrochloride can be used for the research of depression .
    Iprindole hydrochloride

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