1 Result for "

NSC19912

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NSC19912" in MCE Product Catalog:

Cat. No.: HY-121255
CAS No.: 482-22-4
Purity:  ≥99.0%
Synonyms: (R)-Cryptopleurine; NSC 19912
Target:  

TMV

Research Areas:  

Cancer

(–)-Cryptopleurine is an alkaloid that has been found in Lauraceae and has diverse biological activities. It inhibits the growth of human A375 melanoma, A431 epidermoid carcinoma, A549 lung, MES-SA uterine sarcoma, and MCF-7 breast cancer cells (IC50=3 nM for all).2 (–)-Cryptopleurine inhibits hypoxia-induced gene expression in a hypoxia response element (HRE) reporter assay (IC50=8.7 nM).3 (–)-Cryptopleurine (500 μg/mL) prevents lesion formation in tobacco (N. tabacum) plants infected with tobacco mosaic virus (TMV). It also inhibits protein synthesis by yeast and mammalian ribosomes.
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