1 Result for "

NSC339614

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NSC339614" in MCE Product Catalog:

Cat. No.: HY-148611
CAS No.: 1135037-53-4
Target:  

iGluR

Research Areas:  

Neurological Disease

NSC339614 potassium is a selective GluN1/GluN2C and GluN1/GluN2D receptor enhancer with the activity of enhancing neuronal responses to specific NMDA receptors. NSC339614 potassium can selectively enhance the signaling of GluN1/GluN2C and GluN1/GluN2D receptors without affecting other NMDA receptors. The mechanism of action of NSC339614 potassium does not compete with agonists of L-glutamate or glycine, nor does it depend on membrane potential. The activity of NSC339614 potassium depends on the specific structure of the agonist ligand binding domain, showing its potential as a novel pharmacological agent for studying the function of NMDA receptor subtypes and providing new lead compounds for a variety of neurological diseases .
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