1 Result for "

OCI-LY1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "OCI-LY1" in MCE Product Catalog:

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Cat. No.: HY-178777
CAS No.: 3084696-50-1
Target:  

PROTACs BCL6

Research Areas:  

Cancer

BCL6-760 is an orally active BCL-6 PROTAC degrader with an EC50 of 0.8 nM. BCL6-760 only degrades BCL6 and has no effect on other CRBN substrates. BCL6-760 demonstrates significant efficacy in the orthotopic xenograft mouse model of OCI-LY-1 tumors. BCL6-760 can be used in the research of diffuse Large B-cell Lymphoma (DLBCL) (Pink: BCL-6 ligand (HY-179317); Blue: CRBN ligand (HY-179305); Black: Linker) [1].
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