1 Result for "

OM153

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "OM153" in MCE Product Catalog:

Cat. No.: HY-145267
CAS No.: 2406278-81-5
Purity:  99.59%
Target:  

PARP Wnt

Research Areas:  

Cancer

OM-153 is a potent and orally active tankyrase inhibitor with IC50s of 13 nM and 2 nM for tankyrase 1 and tankyrase 2 (TNKS1/2), respectively. OM-153 inhibits luciferase-based Wnt/β-catenin signaling reporter activity with an IC50 value of 0.63 nM. OM-153 shows inhibition of Wnt/β-catenin signaling and proliferation in COLO 320DM .
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