1 Result for "

Oleic Acid-2,6-diisopropylanilide

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Oleic Acid-2,6-diisopropylanilide" in MCE Product Catalog:

Cat. No.: HY-120984
CAS No.: 140112-65-8
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol.1 Oleic acid-2,6-diisopropylanilide is an inhibitor of acylCoA:cholesterol acyltransferase with an IC50 of 7 nM.2 When co-administered to rabbits or rats fed a high fat, high cholesterol diet, oleic acid-2,6-diisopropylanilide decreased low density lipoproteins and elevated high density lipoprotein levels when administered at 0.05%.
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