140112-65-8
Chemical Structure
Oleic Acid-2,6-diisopropylanilide
- CAS No.: 140112-65-8
- Formula:C30H51NO
- Molecular Weight:441.73
IUPAC Name: N-(2,6-diisopropylphenyl)oleamide
InChIKey: KIULGBCXKSTGQP-YPKPFQOOSA-N
SMILES: CC(C1=C(C(C(C)C)=CC=C1)N(C(CCCCCCC/C=C\CCCCCCCC)=O)[H])C
Biological Activity: AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol.1 Oleic acid-2,6-diisopropylanilide is an inhibitor of acylCoA:cholesterol acyltransferase with an IC50 of 7 nM.2 When co-administered to rabbits or rats fed a high fat, high cholesterol diet, oleic acid-2,6-diisopropylanilide decreased low density lipoproteins and elevated high density lipoprotein levels when administered at 0.05%.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Oleic Acid-2,6-diisopropylanilide | 99.98% | AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol.1 Oleic acid-2,6-diisopropylanilide is an inhibitor of acylCoA:cholesterol acyltransferase with an IC50 of 7 nM.2 When co-administered to rabbits or rats fed a high fat, high cholesterol diet, oleic acid-2,6-diisopropylanilide decreased low density lipoproteins and elevated high density lipoprotein levels when administered at 0.05%. | ||||||||||||||||||||
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Keywords
