26 Results for "

Oxytocin Receptor Agonist

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "Oxytocin Receptor Agonist" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-17573
CAS No.: 37025-55-1
Target:  

Oxytocin Receptor

Research Areas:  

Neurological Disease Endocrinology

Carbetocin, an oxytocin (OT) analogue, is an oxytocin receptor agonist with a Ki of 7.1 nM. Carbetocin has high affinity to chimeric N-terminus (E1) of the oxytocin receptor (Ki=1.17 μM). Carbetocin has the potential for postpartum hemorrhage research. Carbetocin can crosse the blood-brain barrier and produces antidepressant-like activity via activation of oxytocin receptors in the CNS .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-P3467
CAS No.: 60786-59-6
Research Areas:  

Neurological Disease

(Thr4,Gly7)-Oxytocin, an Oxytocin analogue, is a specific OT receptor agonist. (Thr4,Gly7)-Oxytocin also excites subicular neurons via activation of TRPV1 channels, and depression of K + channels. .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-17573A
CAS No.: 1631754-28-3
Target:  

Oxytocin Receptor

Research Areas:  

Neurological Disease Endocrinology

Carbetocin acetate, an oxytocin (OT) analogue, is an oxytocin receptor agonist with a Ki of 7.1 nM. Carbetocin acetate has high affinity to chimeric N-terminus (E1) of the oxytocin receptor (Ki=1.17 μM). Carbetocin acetate has the potential for postpartum hemorrhage research. Carbetocin acetate can crosse the blood-brain barrier and produces antidepressant-like activity via activation of oxytocin receptors in the CNS .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-15522
CAS No.: 847375-16-0
Target:  

Oxytocin Receptor

Research Areas:  

Neurological Disease

WAY-267464 is a non-peptide oxytocin receptor (OTR) agonist. WAY-267464 can impair social recognition memory in rats through a vasopressin 1A receptor antagonist action. WAY-267464 can be used for the research of psychiatric disorders, such disorders include autism spectrum disorder, schizophrenia, and social anxiety disorder .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-108679
CAS No.: 1432043-31-6
Target:  

Oxytocin Receptor

Research Areas:  

Neurological Disease

WAY-267464 (hydrochloride) is a non-peptide oxytocin receptor (OTR) agonist. WAY-267464 (hydrochloride) can impair social recognition memory in rats through a vasopressin 1A receptor antagonist action. WAY-267464 (hydrochloride) can be used for the research of psychiatric disorders, such disorders include autism spectrum disorder, schizophrenia, and social anxiety disorder .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P0004
CAS No.: 50-57-7
Synonyms: Lysine vasopressin; [Lys8]-Vasopressin
Lysipressin (Lysine vasopressin ; [Lys8]-Vasopressin ) is a neurohypophyseal nonapeptide with dual cardiovascular regulatory activities of peripheral pressor action and central hypotensive action, and it also regulates pain perception in the body. Lysipressin is an Oxytocin Receptor agonist, with a Ki value of 10.2 nM for porcine OT receptor. Lysipressin stimulates contraction of rabbit bladder smooth muscle via V1-vasopressin receptor. The central hypotensive effect of Lysipressin depends on the sympathetic tone pathway. Lysipressin dose-dependently prolongs tail-flick latency in rats, producing a stable central antinociceptive effect. Lysipressin can be used in studies related to cardiovascular regulation, hypertension and pain .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P0004A
CAS No.: 83968-49-4
Synonyms: Lysine vasopressin acetate; [Lys8]-Vasopressin acetate
Lysipressin acetate (Lysine vasopressin acetate; [Lys8]-Vasopressin acetate) is a neurohypophyseal nonapeptide with dual cardiovascular regulatory activities of peripheral pressor action and central hypotensive action, and it also regulates pain perception in the body. Lysipressin acetate is an Oxytocin Receptor agonist, with a Ki value of 10.2 nM for porcine OT receptor. Lysipressin acetate stimulates contraction of rabbit bladder smooth muscle via V1-vasopressin receptor. The central hypotensive effect of Lysipressin acetate depends on the sympathetic tone pathway. Lysipressin acetate dose-dependently prolongs tail-flick latency in rats, producing a stable central antinociceptive effect. Lysipressin acetate can be used in studies related to cardiovascular regulation, hypertension and pain .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P0267
CAS No.: 121062-08-6
Melanotan (MT)-II is a melanocortin receptor agonist. Melanotan (MT)-II activates melanocortin receptor 3 and melanocortin receptor 4, and stimulates the release of central endogenous oxytocin. Melanotan (MT)-II reverses recognition memory impairment, increased anxiety levels and reduced exploratory tendency in zebrafish exposed to short-term high-fat diet. Melanotan (MT)-II improves impaired social behavior indicators in mouse models of autism spectrum disorder. Melanotan (MT)-II induces weight loss, reduces food intake and exerts anorectic effects. Melanotan (MT)-II increases intracavernous pressure and erectile activity in brown rats. Melanotan (MT)-II can be used in studies related to memory impairment, anxiety, reduced exploratory behavior, autism spectrum disorder, obesity and erectile dysfunction .
loading...
    loading...
Cat. No.: HY-124733A
CAS No.: 2245072-21-1
Purity:  98.63%
Target:  

Oxytocin Receptor

Research Areas:  

Neurological Disease

LIT-001 is the first nonpeptide oxytocin receptor (OT-R) agonist (EC50=55 nM; Ki=226 nM). LIT-001 improves social interaction in a mouse model of autism .
loading...
    loading...
Cat. No.: HY-W048739
CAS No.: 312624-65-0
Research Areas:  

Others

Fmoc-α-Me-Leu-OH is a leucine derivative with an Fmoc protecting group, which can be used to synthesize peptides with oxytocin receptor agonist activity .
loading...
    loading...
Cat. No.: HY-153963
Purity:  99.24%
Target:  

Oxytocin Receptor

Research Areas:  

Endocrinology

PF-06655075 is a novel andnon–brain-penetrant oxytocin receptor agonist with increased selectivity for the oxytocin receptor and significantly increased pharmacokinetic stability. PF-06655075 can be used as a tool compound to further explore the role of peripheral oxytocin in behavioral response .
loading...
    loading...
Cat. No.: HY-14778
CAS No.: 820957-38-8
Purity:  98.97%
Synonyms: GSK 221149; GSK 221149A
Target:  

Oxytocin Receptor

Research Areas:  

Neurological Disease Endocrinology

Retosiban (GSK221149A) is a potent, selective, and orally active oxytocin receptor antagonist (Ki (hOT) = 0.65 nM, Ki (rOT) = 4.1 nM) with no detectable agonist activity. Retosiban has nanomolar affinity for the oxytocin receptor with >1400-fold selectivity over the closely related vasopressin receptors. Retosiban inhibits spontaneous and induces uterine contractions. Retosiban can be studied in research for preterm labour .
loading...
    loading...
Cat. No.: HY-108678
CAS No.: 479232-57-0
Purity:  97.7%
TC OT 39 is a synthetic oxytocin analog, as well as a selective agonist of oxytocin receptor (OXTR, EC50=180 nM). TC OT 39 is also an Avprla vasopressin receptor antagonist with an Ki value of 330 nM. TC OT 39 exhibits sedative effects in mouse models .
loading...
    loading...
Cat. No.: HY-P1390
CAS No.: 500170-27-4
Target:  

Vasopressin Receptor

Research Areas:  

Endocrinology

d[Cha4]-AVP is a potent and selective vasopressin (AVP) V1b receptor agonist with a Ki of 1.2 nM for human V1b receptor. d[Cha4]-AVP shows more selective for V1b receptor than human V1a receptor, V2 receptor, and oxytocin receptors .
loading...
    loading...
Cat. No.: HY-P0077
CAS No.: 1190083-57-8
Target:  

Oxytocin Receptor

Research Areas:  

Endocrinology

Merotocin is a selective, short-acting peptidic oxytocin receptor agonist. Merotocin can be used to support lactation .
loading...
    loading...
Cat. No.: HY-172814A
CAS No.: 3039925-73-7
OT-R agonist 1 TFA (compound 5) is an oxytocin receptor agonist with an EC50 of 0.39 nM. OT-R agonist 1 TFA shows V1A antagonist activity with an EC50 of 2432 nM and can be used for study of CNS disorders .
loading...
    loading...
Cat. No.: HY-153963A
Target:  

Oxytocin Receptor

Research Areas:  

Endocrinology

PF-06655075 (TFA) is the TFA form of PF-06655075 (HY-153963). PF-06655075 is a novel andnon–brain-penetrant oxytocin receptor agonist with increased selectivity for the oxytocin receptor and significantly increased pharmacokinetic stability. PF-06655075 can be used as a tool compound to further explore the role of peripheral oxytocin in behavioral response .
loading...
    loading...
Cat. No.: HY-P10325
CAS No.: 339532-29-5
Kalata B7 is a cyclotide that can be isolated from Oldenlandia affinis DC (Rubiaceae) and possesses membrane-permeating capabilities. Kalata B7 is also a partial agonist of oxytocin and vasopressin V1a receptors .
loading...
    loading...
Cat. No.: HY-124733
CAS No.: 2245072-20-0
Target:  

Oxytocin Receptor

Research Areas:  

Neurological Disease

LIT-001 free base is the first nonpeptide oxytocin receptor (OT-R) agonist (EC50=55 nM; Ki=226 nM). LIT-001 free base improves social interaction in a mouse model of autism .
loading...
    loading...
Cat. No.: HY-P1390A
Target:  

Vasopressin Receptor

Research Areas:  

Endocrinology

d[Cha4]-AVP TFA is a potent and selective vasopressin (AVP) V1b receptor agonist with a Ki of 1.2 nM for human V1b receptor. d[Cha4]-AVP TFA shows more selective for V1b receptor than human V1a receptor, V2 receptor, and oxytocin receptors .
loading...
    loading...