60786-59-6
Chemical Structure
(Thr4,Gly7)-Oxytocin
- CAS No.: 60786-59-6
- Formula:C39H61N11O12S2
- Molecular Weight:940.10
InChIKey: XQAKKLKDUOWUIU-IKNHWLCZSA-N
SMILES: O=C(N[C@@](C(N[C@@](C(N[C@H](C(N[C@@H](CSSC[C@@H](C(N1)=O)N)C(NCC(N[C@@H](CC(C)C)C(NCC(N)=O)=O)=O)=O)=O)CC(N)=O)=O)([H])[C@H](O)C)=O)([H])[C@@H](C)CC)[C@@H]1CC2=CC=C(C=C2)O
Biological Activity: (Thr4,Gly7)-Oxytocin, an Oxytocin analogue, is a specific OT receptor agonist. (Thr4,Gly7)-Oxytocin also excites subicular neurons via activation of TRPV1 channels, and depression of K+ channels. [1][2].
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(Thr4,Gly7)-Oxytocin | 99.89% | (Thr4,Gly7)-Oxytocin, an Oxytocin analogue, is a specific OT receptor agonist. (Thr4,Gly7)-Oxytocin also excites subicular neurons via activation of TRPV1 channels, and depression of K+ channels. . | ||||||||||||||||||||
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- [1]. Lily R Barrett, et al. Oxytocin activation of paraventricular thalamic neurons promotes feeding motivation to attenuate stress-induced hypophagia. Neuropsychopharmacology. 2021 Apr;46(5):1045-1056. [Content Brief]
- [2]. Binqi Hu, et al. Activation of Oxytocin Receptors Excites Subicular Neurons by Multiple Signaling and Ionic Mechanisms. Cereb Cortex. 2021 Mar 31;31(5):2402-2415. [Content Brief]
Keywords