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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
P19As
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "P19As" in MCE Product Catalog:
Cat. No.: HY-180981
CAS No.: 2635386-55-7
P19As is a BCR-ABL PROTAC degrader based on Asciminib (HY-104010), with a DC50 value of approximately 200 nM for the wild-type BCR-ABL protein. P19As can degrade the T315I mutant and exhibits potent anti-proliferative activity in BaF3-BCR-ABL (T315I) cells. P19As can be used for the study of chronic myeloid leukemia and acute lymphoblastic leukemia .
Cat. No.: HY-180982
CAS No.: 3106065-83-9
Research Areas:
Asciminib-NH2 is a BCR-ABL ligand and can be used for the synthesis of PROTACs, such as P19As (HY-180981) .
Cat. No.: HY-180978
Target:
Research Areas:
H2N-PEG3-C2-Trizole-C3-COOH is a is a PEG-based PROTAC linker that can be used for the synthesis of PROTACs, such as P19As (HY-180981) and P19P (HY-180977) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
