19 Results for "

P388 mouse leukemia cells

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "P388 mouse leukemia cells" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-N0128
CAS No.: 515-03-7
Sclareol is isolated from Salvia sclarea with anticarcinogenic activity. Sclareol shows strong cytotoxic activity against mouse leukemia (P-388), human epidermal carcinoma (KB) cells and human leukemia cell lines. Sclareol induces cell apoptosis .
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Cat. No.: HY-125037
CAS No.: 1190948-58-3
Diptoindonesin G is a 2-arylbenzofuran derivative and a modulator of estrogen receptor and HSP90 middle domain. Diptoindonesin G exhibits strong cytotoxicity against mouse leukemia P-388 cells with an IC50 of 13.2 μM. Diptoindonesin G has antitumor activity and can be used in the research of tumors such as breast cancer .
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Cat. No.: HY-114648
CAS No.: 339300-34-4
Target:  

Bacterial

Research Areas:  

Infection Cancer

AJI-9561 is a benzoxazole derivative produced by Streptomyces sp. AJI-9561 exhibits cytotoxicity and antibacterial activity. AJI-9561 inhibits the proliferation of Jurkat T cells and mouse P388 leukemia cells, with its IC50 being 0.88 and 1.63 μM respectively. AJI-9561 can be used for research on anti-cancer and antibacterial properties .
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Cat. No.: HY-167671
CAS No.: 135261-89-1
BE-10988 is a DNA topoisomerase inhibitor. BE-10988 inhibits the growth of Doxorubicin (HY-15142A)-resistant and vincristine-resistant P388 mouse leukemia cell lines by increasing the formation of DNA topoisomerase complexes .
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Cat. No.: HY-118726
CAS No.: 244616-85-1
Luotonin F is an alkaloid found in the aerial parts of the P. nigellastrum Bunge. Luotonin F shows cytotoxic activity against mouse leukemia P-388 cells by inhibiting human topoisomerase II .
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Cat. No.: HY-129752
CAS No.: 74720-33-5
Piperafizine B exhibits slightly cytotoxicity in moser cells, P388 cells and Vincristine (VCR) (HY-N0488)-resistant P388 cells (IC50s is 23.8, 22.6 and 23.7 μg/mL, respectively). Piperafizine B exhibits synergistic effects with Vincristine, enhances the VCR-induced cytotoxicity and ameliorates the leukemia in mouse model .
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Cat. No.: HY-N0128R
CAS No.: 515-03-7
Sclareol (Standard) is the analytical standard of Sclareol. This product is intended for research and analytical applications. Sclareol is isolated from Salvia sclarea with anticarcinogenic activity. Sclareol shows strong cytotoxic activity against mouse leukemia (P-388), human epidermal carcinoma (KB) cells and human leukemia cell lines. Sclareol induces cell apoptosis .
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Cat. No.: HY-N14095
CAS No.: 97412-76-5
Curromycin A has antibacterial activity against Gram-positive bacteria such as Bacillus subtilis. Curromycin A can inhibit the replication of human immunodeficiency virus (HIV), inhibit mouse melanoma B16 and leukemia P388 cells .
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Cat. No.: HY-N14110
CAS No.: 97412-77-6
Curromycin B has antibacterial activity against Gram-positive bacteria such as Bacillus subtilis. Curromycin B can inhibit the replication of human immunodeficiency virus (HIV), inhibit mouse melanoma B16 and leukemia P388 cells .
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Cat. No.: HY-N14496
CAS No.: 150829-93-9
Nisamycin has stronger anti-Gram-positive bacteria and weaker anti-fungal and individual Gram-negative bacteria activities. Nisamycin has weak cytotoxic effect. The IC50 of mouse leukemia P388 cells is 4.8 μg/mL .
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Cat. No.: HY-123325
CAS No.: 132412-65-8
Kapurimycin A1 is an anbitiotic that can be isolated from Streptomyces. Kapurimycin A1 has a significant inhibitory effect on Gram-positive bacteria, exhibits cytotoxicity to cultured mammalian cells, and shows strong antitumor activity against the mouse leukemia P388 cell line .
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Cat. No.: HY-137936
CAS No.: 83058-94-0
Target:  

Antibiotic

Research Areas:  

Infection

Terrecyclic acid is a sesquiterpene originally isolated from A. terreus with antibiotic and anticancer activity. It is active against S. aureus, B. subtilis, and M. roseus (MICs=25, 50, and 25 μg/mL, respectively). Terrecyclic acid induces a heat shock response, increases levels of reactive oxygen species (ROS), and inhibits NF-κB activity and cell growth in 3T3-Y9-B12 cells.2 In vivo, terrecyclic acid (0.1, 1, and 10 mg/ml) reduces the number of ascitic fluid tumor cells in a mouse model of P388 murine leukemia.
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Cat. No.: HY-W436478
CAS No.: 887927-59-5
Target:  

Drug Derivative

Research Areas:  

Others

(+)-2,5-epi-Goniothalesdiol is an analogue of Goniothalesdiol, which exhibits significant cytotoxicity against P388 mouse leukemia cells and has insecticidal activity. (+)-2,5-epi-Goniothalesdiol can be synthesized starting from D-mannitol (HY-N0378) .
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Cat. No.: HY-117285
CAS No.: 60227-09-0
Synonyms: Lactoquinomycin A; LQM-A
Lactoquinomycin A is a quinone antibiotic. Lactoquinomycin A has the activity of anti-Gram-positive bacteria and some Gram-negative bacteria, but the effect of anti-Gram-negative bacteria is weak and has no effect on fungi. Lactoquinomycin A inhibits a variety of cell lines including lymphoma L5178Y progenitor, Adriamycin resistant, Bleomycin-resistant, human leukemia K562, mouse leukemia L-1210 and mouse leukemia P 388 with ID50 (μg/mL) of 0.02, 0.006, 0.008, 0.033, 0.013 and 0.03, respectively .
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Cat. No.: HY-N14774
CAS No.: 101342-94-3
Lactoquinomycin B is a quinone antibiotic. Lactoquinomycin B has the activity of anti-Gram-positive bacteria and some Gram-negative bacteria, but the effect of anti-Gram-negative bacteria is weak and has no effect on fungi. Lactoquinomycin B inhibits a variety of cell lines including lymphoma L5178Y progenitor, Adriamycin resistant, Bleomycin-resistant, human leukemia K562, mouse leukemia L-1210 and mouse leukemia P 388 with ID50 (μg/mL) of 0.43, 0.21, 0.19, 0.16, 0.2 and 0.12, respectively .
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Cat. No.: HY-159803
CAS No.: 128201-92-3
Synonyms: 6-O-(3-Ethoxypropionyl)-3',4'-O-exo-benzylidenechartreusin
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

IST-622 (6-O-(3-Ethoxypropionyl)-3',4'-O-exo-benzylidenechartreusin) is an anti-tumor agent with significant growth inhibitory activity. IST-622 exhibits significant anti-tumor effects against a variety of mouse tumors such as P388 and L1210 leukemias, B16 melanoma, Lewis lung carcinoma, Colon 26 and Colon 38 adenocarcinomas, and M5076 reticulum cell sarcoma. IST-622 was orally administered and the results showed efficacy in different tumor types. In addition, IST-622 provided significant inhibitory effects against two human tumor xenograft models: large cell lung carcinoma (Lu-116) and gastric adenocarcinoma (St-4). IST-622 also exhibited significant growth inhibitory activity against P388 leukemia in vitro, with a half inhibitory concentration (IC50) more than 20 times lower than CT .
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Cat. No.: HY-N18156
CAS No.: 66052-49-1
29β-Toosendanin is a toosendanin-type limonoid that is found in the root bark of Melia azedarach. 29β-Toosendanin exerts cytotoxic effects on lymphocytic leukemia cells in vitro. 29β-Toosendanin can be used for the research of leukemia .
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Cat. No.: HY-N8255
CAS No.: 73573-17-8
Puupehenone is a cytotoxic and antifungal agent present in various marine sponge species. Puupehenone exerts cytotoxic activity against leukemia, lung cancer, colon cancer and breast cancer cells, and inhibits the growth of Candida albicans. Puupehenone can be used in research related to cancers such as leukemia, lung cancer, colon cancer and breast cancer .
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Cat. No.: HY-182734
CAS No.: 350509-99-8
Target:  

CDK

Research Areas:  

Cancer

BMS-357075 is a pan-CDK inhibitor with CDK1 IC50 18 nM, CDK2 IC50 3 nM, CDK4 IC50 26 nM. BMS-357075 induces cytotoxicity in human ovarian cancer A2780 cells. BMS-357075 exhibits anticancer activity in mice against P388 murine leukemia. BMS-357075 can be used for the research of leukemia .
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