1. Natural Products
  2. Plants Steroids
  3. Meliaceae
  4. Melia azedarach L.
  5. 29β-Toosendanin

29β-Toosendanin is a toosendanin-type limonoid that is found in the root bark of Melia azedarach. 29β-Toosendanin exerts cytotoxic effects on lymphocytic leukemia cells in vitro. 29β-Toosendanin can be used for the research of leukemia.

For research use only. We do not sell to patients.

29β-Toosendanin

29β-Toosendanin Chemical Structure

CAS No. : 66052-49-1

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Description

29β-Toosendanin is a toosendanin-type limonoid that is found in the root bark of Melia azedarach. 29β-Toosendanin exerts cytotoxic effects on lymphocytic leukemia cells in vitro. 29β-Toosendanin can be used for the research of leukemia[1].

In Vitro

29β-Toosendanin (Compound 5) potently inhibits the viability of mouse P388 lymphocytic leukemia cells in vitro with an IC50 of 0.026 μg/mL[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

574.62

Formula

C30H38O11

CAS No.
SMILES

C[C@]12[C@]34[C@]([C@H](C5=COC=C5)C[C@@]3([H])O4)([C@H](C([C@]1([H])[C@]67[C@@]([C@]([C@@H](C[C@@H]6O)OC(C)=O)([C@H](OC7)O)C)([H])C[C@H]2O)=O)OC(C)=O)C

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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29β-Toosendanin
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HY-N18156
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