1 Result for "

PAV104

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "PAV104" in MCE Product Catalog:

Cat. No.: HY-158405
CAS No.: 2923674-83-1
Synonyms: MAV-104
Target:  

14-3-3 Protein SARS-CoV

Research Areas:  

Infection Inflammation/Immunology

PAV-104 (MAV-104) is a host-targeted, pan-respiratory viral assembly inhibitor. PAV-104 targets a small subset of the host protein 14-3-3 within a transient multi-protein complex. PAV-104 inhibits SARS-CoV-2 replication by blocking post-entry viral assembly/budding through interaction with viral nucleocapsid (N) protein and interference with its oligomerization. PAV-104 is orally active in cats and shows favorable pharmacokinetic properties in rats. PAV-104 can be used for the study of COVID-19 and other respiratory viral infections, including Feline Infectious Peritonitis (FIP) .
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