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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
PDDC
" in MedChemExpress (MCE) Product Catalog:
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1 Results for "PDDC" in MCE Product Catalog:
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PDDC is an orally active and blood-brain barrier-penetrant nSMase2 inhibitor. PDDC reduces ceramide production and extracellular vesicle biogenesis/release through enzyme inhibition (IC50 300 nM). PDDC reduces IL-1β-induced release of plasma extracellular vesicles from neurons, oligodendrocytes, and activated microglia, and decreases the ratio of CD11b-positive/IB4-positive extracellular vesicles. PDDC can be used in research related to acute brain injury .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
