1 Result for "

PLX 4104

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PLX 4104" in MCE Product Catalog:

製品番号: HY-182912
CAS 番号: 2851986-77-9
研究分野:  

Cancer

PLX-4104 is an orally active BRD4 molecular glue degrader with a DC50 of 2 nM. PLX-4104 selectively promotes BRD4 degradation via DCAF11 recruitment, triggering ubiquitination and proteasomal breakdown. PLX-4104 inhibits cancer cell proliferation. PLX-4104 induces complete regression of AML xenograft tumors. PLX-4104 can be used for the research of acute myeloid leukemia .
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