3 Results for "

PLX4720

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "PLX4720" in MCE Product Catalog:

17
17 Cited Publications
Cat. No.: HY-51424
CAS No.: 918505-84-7
Target:  

Raf

Research Areas:  

Cancer

PLX-4720 is a potent and selective inhibitor of B-Raf V600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), and 10-fold selectivity for B-Raf V600E than wild-type B-Raf.
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Cat. No.: HY-51424R
CAS No.: 918505-84-7
Target:  

Raf

Research Areas:  

Cancer

PLX-4720 (Standard) is the analytical standard of PLX-4720. This product is intended for research and analytical applications. PLX-4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), and 10-fold selectivity for B-RafV600E than wild-type B-Raf.
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Cat. No.: HY-51424S
CAS No.: 1304096-50-1
PLX-4720-d7 is the deuterium labeled PLX-4720. PLX-4720 is a potent and selective inhibitor of?B-RafV600E?with?an IC50?of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), and 10-fold selectivity for B-RafV600E than wild-type B-Raf .
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