1 Result for "

PROTAC NLRP3 degrader-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PROTAC NLRP3 degrader-1" in MCE Product Catalog:

Cat. No.: HY-186342
CAS No.: 3115501-20-4
PROTAC NLRP3 degrader-1 is a PROTAC degrader targeting NLRP3. PROTAC NLRP3 degrader-1 recruits VHL E3 ubiquitin ligase to form a ternary complex with NLRP3, inducing VHL-dependent ubiquitination and proteasomal degradation of the inflammasome sensor NLRP3. PROTAC NLRP3 degrader-1 reduces IL-1β release. PROTAC NLRP3 degrader-1 can be used for research on NLRP3-related inflammation, metabolic inflammation, and cancer .
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