3 Results for "

PS48

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "PS48" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-15967
CAS No.: 1180676-32-7
Target:  

PDK-1

Research Areas:  

Cancer

PS48 is an activator of PDK1 with an AC50 of 8 μM.
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Cat. No.: HY-13851
CAS No.: 1180676-33-8
Purity:  98.83%
Target:  

PDK-1

Research Areas:  

Others

PS47 is an inactive E-isomer of PS48. PS48 is an activator of PDK1. PS47 can be used as a negative control for PS48 .
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Cat. No.: HY-124308
CAS No.: 1221964-50-6
Target:  

PKC

Research Areas:  

Cancer

PS315, a derivative of PS48 (HY-15967), is an allosteric PKC inhibitor by binding to the PIF-pocket of aPKC and inducing a displacement of the active site residue Lys111. PS315 inhibits the full-length and catalytic domain constructs of PKCζ (IC50=10 μM) and PKCη (IC50=30 μM). PS315 has anti-cancer activity .
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