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Results for "

PTPRO

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

2

Natural
Products

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N1966
    (E)-Osmundacetone
    2 Publications Verification

    		 p38 MAPK PPAR Cancer
    (E)-Osmundacetone is an inhibitor of the MAPK pathway. (E)-Osmundacetone inhibits the activation of the MAPK signaling pathway and restores the expression of PPARα/ACOX1. (E)-Osmundacetone abrogates abnormal cell proliferation, migration and liver metastasis induced by PTPRO silencing in colorectal cancer cells. (E)-Osmundacetone blocks OA-RD17-mediated activation of the MAPK signaling pathway, thereby reducing macrophage proliferation and migration. (E)-Osmundacetone is applicable to relevant research on colorectal cancer .
    (E)-Osmundacetone
  • HY-RS11446
    PTPRO Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    PTPRO Human Pre-designed siRNA Set A contains three designed siRNAs for PTPRO gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    PTPRO Human Pre-designed siRNA Set A
    PTPRO Human Pre-designed siRNA Set A
  • HY-183573
    PTPRO-IN-1

    		Phosphatase Toll-like Receptor (TLR) NF-κB Interleukin Related Inflammation/Immunology
    PTPRO-IN-1 is a selective, orally active PTPRO inhibitor with an IC50 of 0.16 μM. PTPRO-IN-1 exhibits IC50 values of 2.4 μM, 2.33 μM and 2.13 μM against PTPN22, PTP1B and PTPRT, respectively, and shows almost no inhibitory activity against STEP/SSH2. PTPRO-IN-1 inhibits the TLR4/NF-κB signaling pathway in macrophages, ameliorates colonic pathological conditions and suppresses the secretion of pro-inflammatory cytokines by T cells. PTPRO-IN-1 can be used for the research of inflammatory bowel disease .
    PTPRO-IN-1
  • HY-RS11451
    PTPRU Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    PTPRU Human Pre-designed siRNA Set A contains three designed siRNAs for PTPRU gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    PTPRU Human Pre-designed siRNA Set A
    PTPRU Human Pre-designed siRNA Set A
  • HY-N1966R
    (E)-Osmundacetone (Standard)

    		Reference Standards p38 MAPK PPAR Cancer
    (E)-Osmundacetone (Standard) is the analytical standard of (E)-Osmundacetone (HY-N1966). This product is intended for research and analytical applications. (E)-Osmundacetone is an inhibitor of the MAPK pathway. (E)-Osmundacetone inhibits the activation of the MAPK signaling pathway and restores the expression of PPARα/ACOX1. (E)-Osmundacetone abrogates abnormal cell proliferation, migration and liver metastasis induced by PTPRO silencing in colorectal cancer cells. (E)-Osmundacetone blocks OA-RD17-mediated activation of the MAPK signaling pathway, thereby reducing macrophage proliferation and migration. (E)-Osmundacetone is applicable to relevant research on colorectal cancer .
    (E)-Osmundacetone (Standard)

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