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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
Pendrin
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "Pendrin" in MCE Product Catalog:
Cat. No.: HY-W004705
CAS No.: 5344-90-1
Synonyms: 2-Hydroxymethylaniline
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Research Areas:
SLC26A4-IN-1 (compound 1a) is a pendrin/SLC26A4 inhibitor. pendrin is a Cl -/HCO3 - exchanger .
Cat. No.: HY-RS21256
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Slc26a4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc26a4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P702440
Purity: Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: Pendrin; Sodium-independent chloride/iodide transporter; Solute carrier family 26 member 4
Cat. No.: HY-W015787
CAS No.: 7768-28-7
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Target:
Cat. No.: HY-184898
CAS No.: 2128304-65-2
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PDSinh-C01 is a reversible, non-competitive pendrin (SLC26A4) inhibitor with an IC50 of 2.5 μM. PDSinh-C01 inhibits pendrin-mediated Cl −/SCN − exchange activity, reduces cell counts, protein levels, and pro-inflammatory cytokine production in bronchoalveolar lavage fluid. PDSinh-C01 can be used in research related to acute lung injury and cystic fibrosis .
Cat. No.: HY-184897
CAS No.: 312724-83-7
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YS-01 is an inhibitor of pendrin (SLC26A4) with pulmonary protective activity. YS-01 inhibits pendrin-mediated anion exchange activity, reduces pendrin expression, and suppresses the activation of NF-κB and the production of proinflammatory cytokines. YS-01 alleviates lipopolysaccharide-induced and ventilator-induced lung injury. YS-01 attenuates ovalbumin-induced airway hyperresponsiveness, inflammatory infiltration, epithelial thickening and goblet cell hyperplasia, and reduces eosinophil and neutrophil counts. YS-01 decreases MUC5AC transcription levels induced by IL-4, reverses the reduction of airway surface liquid volume, and inhibits the increase of apical SCN − concentration in epithelial cells. YS-01 can be used in studies related to lung injury and allergic asthma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
