Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
60 Results for "
Peptide mimic
" in MedChemExpress (MCE) Product Catalog:
Products (60)
60 Results for "Peptide mimic" in MCE Product Catalog:
22
22 Publications Verification
Cat. No.: HY-P1439
CAS No.: 1449566-36-2
Target:
Research Areas:
22
22 Publications Verification
Cat. No.: HY-P1439A
Target:
Research Areas:
5
5 Cited Publications
Synonyms: AKR-501 maleate; E5501 maleate; YM477 maleate
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Avatrombopag (AKR-501) maleate is an orally active, non-peptide thrombopoietin receptor (TPO receptor) agonist (EC50: 3.3 nM). Avatrombopag maleate mimics the biological activity of TPO. Avatrombopag maleate increases platelet production by activating intracellular signaling systems and promotes the production of platelets and megakaryocytes from hematopoietic precursor cells. Avatrombopag maleate is a substrate for cytochrome P450 (CYP) 2C9 and CYP3A .
2
2 Cited Publications
Cat. No.: HY-P1075
CAS No.: 261969-05-5
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P2294A
Target:
Research Areas:
Cat. No.: HY-P0102
CAS No.: 823202-99-9
Target:
Research Areas:
Target:
Research Areas:
SUN B8155, a non-peptide agonist of calcitonin (CT) receptor, selectively mimics the biological actions of calcitonin. Calcitonin, a 32-amino acid peptide hormone secreted mainly from the thyroid gland, plays an important role in maintaining bone homeostasis .
Cat. No.: HY-P3732
CAS No.: 332179-76-7
Cat. No.: HY-P11017
CAS No.: 1152066-26-6
Research Areas:
Target:
Research Areas:
CMF019 is an orally active, potent and small molecule agonist at Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ with pKi values of 8.58, 8.49 and 8.71 for human, rat, and mouse, respectively. CMF019 mimics the beneficial cardiovascular actions of apelin in rodents . Apelin receptor (APJ) is a G protein-coupled receptor (GPCR) activated by the endogenous peptide apelin. CMF019 is promising for research of chronic diseases, such as, pulmonary arterial hypertension .
Cat. No.: HY-P5217
Target:
Research Areas:
Cat. No.: HY-P10605
CAS No.: 496856-73-6
Cat. No.: HY-P2518
CAS No.: 141136-85-8
Research Areas:
Cat. No.: HY-P4371
CAS No.: 177942-21-1
Target:
Research Areas:
Target:
Research Areas:
MFN2 agonist-1 is an allosteric agonist of mitofusin 2 (MFN2) with an EC50 of 3 nM. MFN2 agonist-1 mimics the MFN2 HR1 peptide to compete for HR2, disrupt the HR1-HR2 autoinhibitory interaction, stabilize the open conformation of MFN2, and promote GTP hydrolysis and mitochondrial fusion. MFN2 agonist-1 acts in a manner dependent on endogenous MFN1 or MFN2, and does not impair cell viability. MFN2 agonist-1 reverses mitochondrial fragmentation, depolarization, aggregation and axonal transport defects, restores bidirectional movement and improves enhanced autophagy. MFN2 agonist-1 is used in studies related to Charcot-Marie-Tooth disease type 2A, Alzheimer's disease, Parkinson's disease and Huntington's disease .
Cat. No.: HY-P2207
CAS No.: 138531-07-4
Target:
Research Areas:
Cat. No.: HY-P10495A
Target:
Research Areas:
PDK1-IN-RS2 is a mimic of peptide docking motif (PIFtide) and is a substrate-selective PDK1 inhibitor with a Kd of 9 μM. PDK1-IN-RS2 suppresses the activation of the downstream kinases S6K1 by PDK1 .
Cat. No.: HY-P5253
CAS No.: 1374396-34-5
Target:
Research Areas:
Cat. No.: HY-P6365B
CAS No.: 452782-06-8
Synonyms: D-4F
Target:
Research Areas:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
