MFN2 agonist-1
Based on 1 Customer Validation
MFN2 agonist-1 (B-A/l) potently stimulates mitochondrial fusion in mitofusin 2 (MFN2)-deficient cells. MFN2 agonist-1 reverses mitochondrial “clumping” (formation of static mitochondrial aggregates) and restores mitochondrial motility in cultured mouse neurons expressing the CMT2A mutant MFN2 T105M.
For research use only. We do not sell to patients.
- Purity: 98.84%
- CAS No.: 2230047-87-5
- Formula: C21H29N5OS
- Molecular Weight:399.55
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 2230047-87-5
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Appearance Solid
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Molecular Weight 399.55
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Formula C21H29N5OS
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Color White to off-white
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SMILES
O=C(NC1C(C)CCCC1)NCCSC2=NN=C(C3CC3)N2C4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (125.14 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5028 mL | 12.5141 mL | 25.0282 mL | 62.5704 mL |
| 5 mM | 0.5006 mL | 2.5028 mL | 5.0056 mL | 12.5141 mL | |
| 10 mM | 0.2503 mL | 1.2514 mL | 2.5028 mL | 6.2570 mL | |
| 15 mM | 0.1669 mL | 0.8343 mL | 1.6685 mL | 4.1714 mL | |
| 20 mM | 0.1251 mL | 0.6257 mL | 1.2514 mL | 3.1285 mL | |
| 25 mM | 0.1001 mL | 0.5006 mL | 1.0011 mL | 2.5028 mL | |
| 30 mM | 0.0834 mL | 0.4171 mL | 0.8343 mL | 2.0857 mL | |
| 40 mM | 0.0626 mL | 0.3129 mL | 0.6257 mL | 1.5643 mL | |
| 50 mM | 0.0501 mL | 0.2503 mL | 0.5006 mL | 1.2514 mL | |
| 60 mM | 0.0417 mL | 0.2086 mL | 0.4171 mL | 1.0428 mL | |
| 80 mM | 0.0313 mL | 0.1564 mL | 0.3129 mL | 0.7821 mL | |
| 100 mM | 0.0250 mL | 0.1251 mL | 0.2503 mL | 0.6257 mL |
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