1 Result for "

Pirtenidine

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Pirtenidine" in MCE Product Catalog:

Cat. No.: HY-111989
CAS No.: 103923-27-9
Target:  

Bacterial Fungal

Research Areas:  

Infection Inflammation/Immunology

Pirtenidine free base is a broad-spectrum antibacterial and anti-plaque agent. Pirtenidine free base exhibits bactericidal activity against oral plaque bacteria in vitro and inhibits plaque formation. Pirtenidine free base inhibits the growth, budding, germ tube formation and buccal epithelial cell adhesion of Candida albicans and Saccharomyces cerevisiae, reduces the oxygen uptake rate of yeast, and impairs mitochondrial respiratory function. Pirtenidine free base disrupts the integrity of fungal cell wall and membrane, leading to cytoplasmic leakage, cell shrinkage, and lysis. Pirtenidine free base binds tightly to mucosal surfaces in vivo with low systemic exposure. Pirtenidine free base can be used in studies related to dental plaque, fungal infections and oral candidiasis .
loading...
    loading...