1 Result for "

Prinaberel

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Prinaberel" in MCE Product Catalog:

4
4 Cited Publications
Art. -Nr.: HY-14933
CAS. Nr.: 524684-52-4
Reinheit:  98.05%
Synonyms: ERB-041
Forschungsgebiete:  

Cancer

Prinaberel (ERB-041) is a potent and selective estrogen receptor (ER) β agonist with IC50s of 5.4, 3.1 and 3.7 nM for human, rat and mouse ERβ, respectively. Prinaberel displays >200-fold selectivity for ERβ over ERα. Prinaberel is a potent skin cancer chemopreventive agent that acts by dampening the WNT/β-catenin signaling pathway. Prinaberel induces ovarian cancer apoptosis .
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