1 Result for "

ProTx-III

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "ProTx-III" in MCE Product Catalog:

Cat. No.: HY-P5153
CAS No.: 1808297-63-3
Synonyms: μ-TRTX-Tp1a
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

ProTx-III is a selective and potent inhibitor of voltage-gated sodium channel Nav1.7, with an IC50 of 2.1 nM. ProTx-III is a spider venom peptide isolated from the venom of the Peruvian green velvet tarantella. ProTx-III has a typical inhibitor cystine knot motif (ICK). ProTx-III is able to reverse the pain response. ProTx-III can be used to study diseases such as chronic pain, epilepsy, and arrhythmia .
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