1 Result for "

R1530

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "R1530" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-13737
CAS No.: 882531-87-5
Purity:  98.29%
Target:  

Apoptosis VEGFR FGFR Mitosis

Research Areas:  

Cancer

R1530 is a highly potent, orally active, dual-acting mitosis/angiogenesis inhibitor, with anti-tumor and anti-angiogenic activities. R1530 is a multikinase inhibitor which binds to 31 kinases with Kd values of <500 nM. R1530 inhibits VGFR2 and FGFR1 with IC50 of 10 nM and 28 nM, respectively. R1530 triggers apoptosis (mitotic catastrophe) or senescence .
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