1 Result for "

RG-6512

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "RG-6512" in MCE Product Catalog:

Zemocimig
Zemocimig
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Referencia número: HY-P991169
No. CAS: 2955620-21-8
Synonyms: NXT007; RG6512; RO7589655

Target:  

Factor Xa Thrombin

Áreas de investigación:  

Cardiovascular Disease

Zemocimig (NXT007) is an activated factor VIII mimetic antibody. Zemocimig binds to FX, FIXa and their activated forms to form a ternary complex, bridges FIXa and FX on the phospholipid surface, and restores intrinsic prothrombinase activity. Zemocimig induces thrombin generation, acts as a procoagulant, antifibrinolytic agent and hemostatic agent, and can shorten aPTT, increase fibrin deposition, correct clotting time, and reduce bleeding parameters. Zemocimig is applicable to the research of hemophilia A .
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