1 Result for "

RO8191

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RO8191" in MCE Product Catalog:

29
29 Cited Publications
Cat. No.: HY-W063968
CAS No.: 691868-88-9
Synonyms: CDM-3008; RO4948191
Target:  

IFNAR JAK STAT HCV HBV

Research Areas:  

Infection

RO8191 (CDM-3008), an imidazonaphthyridine compound, is an orally active and potent interferon (IFN) receptor agonist. RO8191 directly binds to IFNα/β receptor 2 (IFNAR2) and activates IFN-stimulated genes (ISGs) expression and JAK/STAT phosphorylation. RO8191 shows antiviral activity against both HCV and EMCV with an IC50 of 200 nM for HCV replicon . RO8191 is a cccDNA modulator (CDM) through interferon-like activity and has anti-HBV activity .
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