2 Results for "

RSV-IN-5

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "RSV-IN-5" in MCE Product Catalog:

Cat. No.: HY-146108
CAS No.: 2415018-86-7
Target:  

RSV

Research Areas:  

Infection

RSV-IN-5 (Compound 4) is a potent dual inhibitor of wild-type and mutant respiratory syncytial virus (RSV) fusion proteins. RSV-IN-5 exhibits potent anti-RSV activities against not only wild-type A2 F protein (EC50=2.0 nM), but also D486N-mutant F protein (EC50=8.1 nM) .
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Cat. No.: HY-154968
CAS No.: 851658-28-1
Target:  

RSV

Research Areas:  

Infection

RSV L-protein-IN-5 (compound E) is a potent inhibitor of Respiratory syncytial virus (RSV) (EC50=0.1 μM). RSV L-protein-IN-5 inhibits Polymerase (IC50=0.66 μM),and blocks RSV mRNA synthesis by inhibiting guanylation of viral transcripts. RSV L-protein-IN-5 shows moderate cytotoxicity (CC50=10.7 μM,HEp-2),also exhibits activity and lowers virus titers in mouse models of RSV infection .
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