2 Results for "

Recombinant GCase (glucocerebrosidase)

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Recombinant GCase (glucocerebrosidase)" in MCE Product Catalog:

Cat. No.: HY-109514
CAS No.: 154248-97-2
Synonyms: Recombinant GCase (glucocerebrosidase)
Target:  

Glycosidase

Imiglucerase is a recombinant human glucocerebrosidase that glucosylceramide to glucose and ceramide. Imiglucerase can be used for the study of type 1 (non-neuronopathic) and type 3 (chronic neuronopathic) Gaucher's disease .
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Cat. No.: HY-131570
CAS No.: 1997359-63-3
Target:  

Glycosidase

Research Areas:  

Neurological Disease

JZ-4109 is a β-Glucocerebrosidase (GCase) modulator with an IC50 of 8 nM for wild-type recombinant GCase. JZ-4109 binds to an allosteric site at the GCase dimer interface, stabilizes wild-type and GCase N370S mutant GCase, induces GCase dimerization. JZ-4109 increases GCase protein abundance. JZ-4109 can be used for the research of Parkinson's diseas .
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