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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
Ribavirin 5'-triphosphate ammonium
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "Ribavirin 5'-triphosphate ammonium" in MCE Product Catalog:
Cat. No.: HY-134016B
CAS No.: 332153-24-9
Target:
Research Areas:
Ribavirin 5'-triphosphate ammonium is an inhibitor of the dengue virus NS5 2'-O-methyltransferase NS5 domain (NS5MTaseDV) (IC50 = 101 μM; Kd = 55 μM). Ribavirin 5'-triphosphate ammonium blocks RNA cap methylation by competitively binding to the GTP-binding site of NS5MTaseDV, thereby inhibiting the viral mRNA 2'-O-methyltransferase activity. Ribavirin 5'-triphosphate ammonium can be used for research on dengue fever .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
