Search Result
Results for "
Root growth
" in MedChemExpress (MCE) Product Catalog:
9
Biochemical Assay Reagents
6
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N1964
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Gibberellin A3
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Environmental Pollutants
Drug Derivative
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Metabolic Disease
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Gibberellic acid (GA3) is a natural plant growth regulator with oral bioactivity. Gibberellic acid governs multiple plant developmental events, including seed germination, cell elongation, floral organ formation, and rice spikelet fertility. Gibberellic acid optimizes root morphology and secondary metabolite production in Echinacea purpurea hairy roots, and serves as a bioactive seed priming agent to improve chilling stress tolerance in chickpea. Gibberellic acid mediates modulation of enzyme activity and secondary metabolism in plants and exerts tissue-specific regulatory effects on antioxidant systems and lipid peroxidation in rats. Gibberellic acid can be used in studies of plant growth, metabolism, and abiotic stress responses .
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- HY-N0186
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Indolebutyric acid
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Environmental Pollutants
Endogenous Metabolite
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Others
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Indole-3-butyric acid (3-indolebutyric acid) is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate. Indole 3-butyric acid is an auxin precursor, and is converted to indole 3-acetic acid (IAA) in a peroxisomal β-oxidation process .
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- HY-N1381
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Apoptosis
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Inflammation/Immunology
Cancer
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Periplocin is a cardiotonic steroid isolated from root-bark Periploca sepium Bunge. Periplocin promotes tumor cell apoptosis and inhibits tumor growth. Periplocin has the potential to facilitate wound healing through the activation of Src/ERK and PI3K/Akt pathways mediated by Na/K-ATPase .
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- HY-N0373
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Licochalcone B
Maximum Cited Publications
12 Publications Verification
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Amyloid-β
Apoptosis
NOD-like Receptor (NLR)
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Neurological Disease
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Licochalcone B is an extract from the root of Glycyrrhiza uralensis. Licochalcone B inhibits amyloid β (42) self-aggregation (IC50=2.16 μM) and disaggregate pre-formed Aβ42 fibrils, reduce metal-induced Aβ42 aggregation through chelating metal ionsLicochalcone B inhibits phosphorylation of NF-κB p65 in LPS signaling pathway. Licochalcone B inhibits growth and induces apoptosis of NSCLC cells. Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7‐NLRP3 interaction .
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- HY-N1458
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- HY-131683
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ES9-17
1 Publications Verification
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Dynamin
Clathrin
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Others
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ES9-17 is an analog of ES9 (endosidin9), which is an inhibitor of clathrin heavy chain (CHC). ES9-17 is an inhibitor of clathrin-mediated endocytosis (CME), a major route for internalization of plasma membrane proteins and molecules from the extracellular environment in plants. ES9-17 inhibits the uptake of transferrin and FM4-64. ES9-17 also inhibits root growth of Arabidopsis seedings .
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- HY-136409
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C10-HSL
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Bacterial
Reactive Oxygen Species (ROS)
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Infection
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N-decanoyl-L-homoserine lactone (C10-HSL) is a N-acyl-homoserine lactone (AHL) N-decanoyl-L-homoserine lactone can inhibit primary root growth in Arabidopsis. N-decanoyl-L-homoserine lactone triggers a transient and immediate increase in the concentrations of cytosolic free Ca 2+ and reactive oxygen species (ROS), increases the activity of mitogen-activated protein kinase 6 (MPK6), and induces nitric oxide (NO) production in Arabidopsis roots .
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- HY-W116336D
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Biochemical Assay Reagents
Fungal
Bacterial
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Infection
Cancer
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Zinc oxide, <100 nm particle size is a nitrate reductase modulator and growth promoter with plant stress resistance activity and oral toxicity. Zinc oxide, <100 nm particle size acts as a nutrient source for maize plants. By enhancing nitrate reductase activity and reducing free proline levels, it significantly improves plant height, root length and dry matter weight of maize, and its growth-promoting effect is comparable to that of traditional zinc sulfate fertilizer. Zinc oxide, <100 nm particle size induces anemia-related and persistent tissue inflammatory damage, leading to obvious histopathological adverse reactions in the stomach, pancreas, eyes and prostate of rats. Zinc oxide, <100 nm particle size acts as a non-toxic antibacterial agent and selective cytotoxin against multiple bacteria, fungi and spores .
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- HY-142006A
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(±)-JA-L-Ile
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Phytohormone
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Others
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(±)-Jasmonic-L-isoleucine ((±)-JA-L-Ile) is a mixture of (±)-Jasmonic acid (HY-122464) and isoleucine isomers. (±)-Jasmonic-L-isoleucine is a phytohormone that participates in the jasmonic acid signaling pathway. (±)-Jasmonic-L-isoleucine regulates biological processes in plants, including defense responses, growth and development, and stress tolerance .
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- HY-18570B
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NAA
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Biochemical Assay Reagents
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Others
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1-Naphthaleneacetic acid,suitable for plant cell culture (NAA) is a plant growth hormone. 1-Naphthaleneacetic acid,suitable for plant cell culture promotes plant growth and induces root cluster formation. Naphthaleneacetic acid,suitable for plant cell culture is applicable for plant cell culture .
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- HY-N9599
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Fungal
Endogenous Metabolite
Parasite
Insecticide
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Infection
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Roridin A acts as an inhibitor of pollen development in Arabidopsis thaliana and nematicide. Roridin A is isolated from the fungus Cylindrocarpon sp. Roridin A delays the flowering time of Arabidopsis thaliana, inhibits pollen development and stem elongation, and blocks plant growth. Roridin A induces larval death of the southern root-knot nematode (Meloidogyne incognita) .
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- HY-136403
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Phytohormone
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Others
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TIS108 is a triazole-type strigolactone biosynthesis inhibitor. TIS108 inhibits Arabidopsis embryogenesis and root hair growth, and promotes shoot branching. TIS108 can also increase the gibberellin content in Gastrodia elata. TIS108 can be used in the research of plant growth and development as well as plant responses to the environment .
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- HY-136302
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Phytohormone
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Others
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Karrikinolide is a plant-active compound. Karrikinolide can be extracted from smoke water (SW). Karrikinolide promotes total Cytokinin production. Plants treated with Karrikinolide exhibit superior growth in terms of rooting, leaf and bulb size, and fresh weight .
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- HY-B0503
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Thiouracil
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NO Synthase
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Endocrinology
Cancer
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2-Thiouracil (Thiouracil) is a selective neuronal nitric oxide synthase (nNOS) inhibitor with a Ki value of 20 μM. 2-Thiouracil antagonizes BH4-induced nNOS dimerization. 2-Thiouracil is also an antithyroid compound and a highly specific melanoma detector. 2-Thiouracil stimulates the growth of pea and corn root segments .
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- HY-B2050
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Environmental Pollutants
Herbicide
Microtubule/Tubulin
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Others
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Trifluralin is a selective, preemergence, soil-applied herbicide providing control of many important annual grass and broadleaf weed species. Trifluralin prevents weed growth by inhibiting root development through the interruption of mitosis. Trifluralin binds to tubulin and results in the failure of spindle apparatus and cell plate formation. Trifluralin inhibits radicle development on roots. Trifluralin inhibits cell mitosis. Trifluralin is considered to be neurotoxic and haematotoxic .
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- HY-W004599
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Herbicide
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Others
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Bicinchoninic acid (compound 8) is an AHAS inhibitor, in an in vivo bioassay targeting the root growth inhibition of rapeseed, at a concentration of 100 μg/mL, it exhibited very low activity, with only a 1.4% root length inhibition rate .
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- HY-151931
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Jasmonyl-ACC
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Phytohormone
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Metabolic Disease
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JA-ACC (Jasmonyl-ACC) is a derivative of 1-aminocyclopropane-1-carboxylic acid (ACC). ACC is the direct precursor of the plant hormone ethylene. JA-ACC inhibits root growth in Arabidopsis and the inhibition is independent of jasmonic acid (JA) signaling .
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- HY-D1084
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- HY-B1918
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Interleukin Related
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Others
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(+)-Bornyl acetate is found in pichtae essential oil (Siberian fir needle oil). (+)-Bornyl acetate has a stronger inhibitory effect on root growth of Arabidopsis seedlings .
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- HY-101404
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Endogenous Metabolite
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Others
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DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.
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- HY-W016289
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3,4,5-Trimethoxyphenol
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Glycosidase
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Others
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Antiarol (3,4,5-Trimethoxyphenol) is a natural compound. Antiarol can be extracted from Cochlospermum vitifolium. Antiarol can be used to study plant seed germination and root and hypocotyl growth .
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- HY-139783
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Environmental Pollutants
Apoptosis
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Others
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3-Campholenyl-2-butanol, a synthetic sandalwood odorant, is a selective olfactory receptor OR2AT4 agonist. 3-Campholenyl-2-butanol prolongs human hair growth ex vivo by decreasing apoptosis and increasing production of the anagen-prolonging growth factor IGF-1 in the outer root sheath (ORS) .
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- HY-117089
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Environmental Pollutants
Fungal
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Infection
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Tetraconazole is a selective irreversible inhibitor of 14-α-sterol demethylase (CYP51) with antifungal activity. Tetraconazole competitively binds to the enzyme to block fungal ergosterol synthesis, resulting in cell membrane damage. The EC50 of tetraconazole against wheat pathogens is 0.382-0.802 mg/L, and the EC50 against onion root tip meristem cell growth is 6.7 mg/L, and (R)-(+)-Tetraconazole is 1.49-1.98 times more active than (S)-(-)-Tetraconazole. Tetraconazole can also induce oxidative stress and chromosomal aberrations in plant cells .
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- HY-N6924
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HIV
PIN1
Fungal
GLUT
Reactive Oxygen Species (ROS)
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Infection
Neurological Disease
Metabolic Disease
Cancer
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Zingibroside R1 is an orally active triterpene saponin with multiple biological activities including antioxidant, anti-inflammatory, antiviral, and metabolic regulatory properties. Zingibroside R1 reduces the expression of PIN family members, inhibits the expression of PLT1/PLT2, WOX5, SHR, and SCR, disrupts auxin transport and distribution, triggers plant ROS responses, and inhibits root growth. Zingibroside R1 extends the lifespan of Caenorhabditis elegans, enhances its heat stress resistance, and improves its motor ability. Hydrogel derivatives of Zingibroside R1 inhibit the proliferation of Candida albicans by binding to its β-1,3-glucan and exhibit antifungal activity. Zingibroside R1 inhibits GLUT1-mediated uptake and alleviates liver injury. Zingibroside R1 can be used in research related to neurodegenerative diseases, vulvovaginal candidiasis, acute liver injury, Ehrlich ascites tumor and HIV-1 infection .
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- HY-N0186A
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Indolebutyric acid potassium
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Endogenous Metabolite
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Others
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Indole-3-butyric acid (Indolebutyric acid) potassium is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate. Indole 3-butyric acid potassium is an auxin precursor, and is converted to indole 3-acetic acid (IAA) in a peroxisomal β-oxidation process .
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- HY-W001940
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Amino Acid Derivatives
Bacterial
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Infection
Cardiovascular Disease
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DL-m-Tyrosine is a non-protein amino acid. DL-m-Tyrosine inhibits microbial growth and spore formation. DL-m-Tyrosine also inhibits root growth in various plants, such as lettuce and Arabidopsis. DL-m-Tyrosine, when used in combination with Carbidopa (HY-B0311), has a potent antihypertensive effect. DL-m-Tyrosine can be used in research on biopesticide design .
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- HY-N0186R
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Indolebutyric acid (Standard)
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Reference Standards
Endogenous Metabolite
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Others
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Indole-3-butyric acid (Standard) is the analytical standard of Indole-3-butyric acid. This product is intended for research and analytical applications. Indole-3-butyric acid (3-indolebutyric acid) is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate. Indole 3-butyric acid is an auxin precursor, and is converted to indole 3-acetic acid (IAA) in a peroxisomal β-oxidation process .
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- HY-N7659A
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Phytohormone
Microtubule/Tubulin
Apoptosis
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Others
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Glucobrassicin potassium is an indole-based anticancer agent and plant growth-regulating hormone. Glucobrassicin potassium exerts its biological activity by disrupting the integrity of microtubule networks in both plant and mammalian cells. At high concentrations, Glucobrassicin potassium inhibits seed germination and root growth; it can also specifically induce apoptosis in mammalian cancer cells and interfere with the intercellular transmission of viruses that rely on microtubules. In plants, Glucobrassicin potassium can be catalyzed by myrosinase to release growth-regulating substances, exhibiting a concentration-dependent growth-regulating effect .
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- HY-N7659
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Phytohormone
Apoptosis
Microtubule/Tubulin
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Cancer
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Glucobrassicin is an indole-based anticancer agent and plant growth-regulating hormone. Glucobrassicin exerts its biological activity by disrupting the integrity of microtubule networks in both plant and mammalian cells. At high concentrations, Glucobrassicin inhibits seed germination and root growth; it can also specifically induce apoptosis in mammalian cancer cells and interfere with the intercellular transmission of viruses that rely on microtubules. In plants, Glucobrassicin can be catalyzed by myrosinase to release growth-regulating substances, exhibiting a concentration-dependent growth-regulating effect .
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- HY-W054259
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N,N'-Difurfuryloxamide; N1,N2-Bis(furan-2-ylmethyl)oxalamide
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Biochemical Assay Reagents
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Others
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BFMO (N,N'-Difurfuryloxamide) is an oxamide derivative and a bidentate ligand. BFMO exhibits plant growth regulatory activity and root growth inhibitory activity. BFMO can promote the copper-catalyzed N-arylation reaction between aniline compounds and cyclic secondary amines, realizing the coupling of (hetero) aryl bromides with (hetero) aryl amines and cyclic secondary amines .
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- HY-N0186B
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IBA
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Biochemical Assay Reagents
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Others
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Indole-3-butyric acid,suitable for plant cell culture (IBA) is a plant auxin and a good rooting agent. Indole-3-butyric acid,suitable for plant cell culture can promote rooting of herbaceous and woody ornamental plants and is used to increase fruiting rate. Indole-3-butyric acid is an auxin precursor that is converted into indole 3-acetic acid (IAA) during peroxisomal β-oxidation. Indole-3-butyric acid,suitable for plant cell culture can be used for cell culture .
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- HY-163311
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Transketolase
Herbicide
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Others
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Transketolase-IN-6 is a potent transketolase inhibitor and a herbicide. Transketolase-IN-6 inhibits root growth of Digitaria sanguinalis, Amaranthus retroflexus, and Setaria viridis. Transketolase-IN-6 shows low phytotoxicity to wheat, maize, soybean, and cotton. Transketolase-IN-6 can be used for the research of herbicidal agent development .
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- HY-175249
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Others
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TKL-IN-2 is a herbicide and SvTKL inhibitor with an IC50 of 0.11 mg/L. TKL-IN-2 binds to the SvTKL active site, interacts with key pocket residues, and inhibits enzyme activity. TKL-IN-2 can be used for the research of weed control in maize, wheat, soybean, and cotton fields .
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- HY-N1964A
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Drug Derivative
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Metabolic Disease
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Gibberellic acid, suitable for plant cell culture (GA3, suitable for plant cell culture) is a natural plant growth regulator with oral bioactivity. Gibberellic acid, suitable for plant cell culture governs multiple plant developmental events, including seed germination, cell elongation, floral organ formation, and rice spikelet fertility. Gibberellic acid, suitable for plant cell culture optimizes root morphology and secondary metabolite production in Echinacea purpurea hairy roots, and serves as a bioactive seed priming agent to improve chilling stress tolerance in chickpea. Gibberellic acid, suitable for plant cell culture mediates modulation of enzyme activity and secondary metabolism in plants and exerts tissue-specific regulatory effects on antioxidant systems and lipid peroxidation in rats. Gibberellic acid, suitable for plant cell culture can be used in studies of plant growth, metabolism, and abiotic stress responses .
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- HY-N1450
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Phospholipase
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Cancer
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Aristolochic acid C is a derivative of Aristolochic acid. Aristolochic acid is a phospholipase A2 (PLA2) inhibitor, which disrupts cortical microtubule arrays and root growth in Arabidopsis .
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- HY-119994
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Protein Arginine Deiminase
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Others
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DFPM activates plant resistance protein signaling in roots, and triggers root growth arrest. DFPM decreases root cell viability in accession Col-0. DFPM is light sensitive in aqueous solutions. DFPM becomes bioactive during light and oxygen-dependent modification .
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- HY-118528
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TGF-β Receptor
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Cancer
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TP0427736 is a selective inhibitor of ALK5 with an IC50 of 2.72 nM. TP0427736 inhibits Smad2/3 phosphorylation in A549 cells. TP0427736 decreases the growth inhibition of human outer root sheath cells .
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- HY-120743
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Biochemical Assay Reagents
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Metabolic Disease
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Triplin is a copper chelator, Triplin perturbs copper ion transport involved in the interaction of RAN1 and ATX1. Triplin suppresses the toxic effects of excess copper ions on plant root growth. Triplin increases the RNA expression of ERF1. Triplin acts through the ethylene signal transduction pathway. Triplin also is a bacterial pore-former .
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- HY-175736
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Herbicide
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Others
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Herbicidal agent 11 (Compound 8a) is a herbicidal agent. Herbicidal agent 11 has significant postemergence herbicidal activities against the monocotyledonous weed Echinochloa crusgalli with inhibition of potent root and stem growth and has a good crop selectivity against wheat, maize, and oilseed rape. Herbicidal agent 11 also has effective inhibitory effects on Digitaria sanguinalis, Eclipta prostrate and Eleusine indica. Herbicidal agent 11 can be used for the development of herbicides .
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- HY-179028
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exo-16,17-Dihydro-gibberellin A5-13-acetate
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Phytohormone
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Others
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DHGA5 (exo-16,17-Dihydro-gibberellin A5-13-acetate) is a GA3β-hydroxylase (OsGA3ox2) inhibitor. DHGA5 inhibits Arabidopsis root growth with an IC50 of 97 μM. DHGA5 also suppresses the elongation of rice second leaf sheath. DHGA5 can alleviate oxidative damage to Arabidopsis seedlings under NaCl salt stress and reduce the accumulation of superoxide anion .
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- HY-N1964R
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Gibberellin A3 (Standard)
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Reference Standards
Drug Derivative
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Metabolic Disease
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Gibberellic acid (Standard) is the analytical standard of Gibberellic acid (GA3) (HY-N1964). This product is intended for research and analytical applications. Gibberellic acidis a natural plant growth regulator with oral bioactivity. Gibberellic acid governs multiple plant developmental events, including seed germination, cell elongation, floral organ formation, and rice spikelet fertility. Gibberellic acid optimizes root morphology and secondary metabolite production in Echinacea purpurea hairy roots, and serves as a bioactive seed priming agent to improve chilling stress tolerance in chickpea. Gibberellic acid mediates modulation of enzyme activity and secondary metabolism in plants and exerts tissue-specific regulatory effects on antioxidant systems and lipid peroxidation in rats. Gibberellic acid can be used in studies of plant growth, metabolism, and abiotic stress responses .
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- HY-175340
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Potassium Channel
TSPO
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Neurological Disease
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Kv7.2/Kv7.3 activator-3 (GRT-X) is an orally active Kv7.2/Kv7.3 and TSPO activator. Kv7.2/Kv7.3 activator-3 activates Kv7.2/Kv7.3, Kv7.4, and Kv7.5 with EC50 values of 0.37, 2.06, and 0.75 μM, respectively, and binds to TSPO with Ki values of 0.07 μM (rat membrane) and 4.60 μM (human U-118 MG cells). Kv7.2/Kv7.3 activator-3 prevents motor neuron degeneration in mice and humans conditioned by ALS/FTD astrocytes. Kv7.2/Kv7.3 activator-3 stimulates dorsal root ganglion axonal growth through TSPO and Kv7.2/3 activation. Kv7.2/Kv7.3 activator-3 has anti-epileptic effects in epileptic seizure models. Kv7.2/Kv7.3 activator-3 reduces pain hypersensitivity in patients with diabetic neuropathy, promotes neuronal survival and regeneration after cervical neuropathy in rats, and accelerates the recovery of normal function of sensory and motor neurons .
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- HY-101404S
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Isotope-Labeled Compounds
Endogenous Metabolite
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Others
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DL-Homocysteine thiolactone-d4 hydrochloride is the deuterium labeled DL-Homocysteine thiolactone (hydrochloride). DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.
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- HY-101404R
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Reference Standards
Endogenous Metabolite
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Others
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DL-Homocysteine thiolactone (hydrochloride) (Standard) is the analytical standard of DL-Homocysteine thiolactone (hydrochloride). This product is intended for research and analytical applications. DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.
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- HY-125698
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Parasite
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Infection
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3-Deoxyaphidicolin exhibits phytotoxic efficacy, that inhibits root growth of lettuce seedlings. 3-Deoxyaphidicolin also exhibits leishmanicidal activity against Leishmania major and Leishmania braziliensis .
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- HY-N15454
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Altertenuol
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Herbicide
Bacterial
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Infection
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Altenuisol is a compound that can be found in the pathogenic fungus of the genus Alternaria in Xanthium italicum. It has herbicidal activity. At a low concentration of Altenuisol (10 μg/mL), it promotes the root growth of Pennisetum alopecuroides and Medicago sativa by 75.2% and 51.0% respectively. At a high concentration of Altenuisol (1000 μg/mL), the inhibition rates of root growth of Pennisetum alopecuroides and Medicago sativa are 52.0% and 42.0% respectively. In addition, Altenuisol is cytotoxic to HeLa cells and also exhibits antibacterial and antioxidant activities. Altenuisol is expected to be used in research in fields such as agricultural weeding, anti - tumor, and anti - infection .
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- HY-N12170
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Others
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Neurological Disease
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Kissoone C (compound 3) is a three-membered ring sesquiterpene isolated from valerian root. Kissoone C can enhance the activity of nerve growth factor (NGF)-mediated neurite outgrowth in PC12D cells .
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- HY-N1450R
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Reference Standards
Phospholipase
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Cancer
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Aristolochic acid C (Standard) is the analytical standard of Aristolochic acid C. This product is intended for research and analytical applications. Aristolochic acid C is a derivative of Aristolochic acid. Aristolochic acid is a phospholipase A2 (PLA2) inhibitor, which disrupts cortical microtubule arrays and root growth in Arabidopsis .
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- HY-162421
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Herbicide
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Others
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SL antagonist 1 (Compound D12) is strigolactones antagonists and can strongly interact with SL receptor proteins.SL antagonist 1 can combat root-parasitic weed infestations. SL antagonist 1 has no side effects on the germination or seedling growth .
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- HY-116498
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Others
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Infection
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Penigequinolone A is an alkaloid isolated from Penicillium. It is lethal to P. penetrans (LD50=100 mg/L) but has no effect on C. elegans at concentrations up to 1000 mg/L.1 Penigequinolone A also accelerates the root growth of rice seedlings in a dose-dependent manner.
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- HY-121801
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Fungal
Microtubule/Tubulin
Mitosis
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Infection
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Zarilamid is a fungicide which is active against a broad spectrum of Oomycete fungi. Zarilamid inhibits nuclear division in germinating zoospore cysts of Phytophthora capsici. Zarilamide inhibits growth of tobacco roots and causes swelling of the root tips, destructs microtubule cytoskeleton and inhibits mitosis .
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- HY-N2021AR
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- HY-N7697BR
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Reference Standards
Others
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Others
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Gibberellic acid (Standard) is the analytical standard of Gibberellic acid. This product is intended for research and analytical applications. Gibberellic Acid is named after the fungus Gibberella fujikuroi. Gibberellic Acid regulates processes in plant development and growth, including seed development and germination, stem and root growth, cell division, and flowering time. Gibberellic Acid also improves plant response to growth stress caused by various environmental stresses, such as cold stress, drought stress, heavy metal stress, etc. Gibberellic Acid also causes increased lipid peroxidation and fluctuations in the antioxidant defense system in rats .
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- HY-122984R
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Herbicide
Reference Standards
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Others
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Diquat (dibromide) (Standard) is the analytical standard of Diquat (dibromide). This product is intended for research and analytical applications. Diquat dibromide is a comprehensive herbicide commonly used in the cultivation of cotton, soybeans, and other crops to combat unwanted weeds. Diquat dibromide has an IC50 of 60 mg/L in the Allium root growth inhibition test .
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- HY-122984S
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Isotope-Labeled Compounds
Herbicide
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Others
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Diquat-d4 (dibromide) is the deuterium labeled Diquat dibromide (HY-122984) . Diquat dibromide is a comprehensive herbicide commonly used in the cultivation of cotton, soybeans, and other crops to combat unwanted weeds. Diquat dibromide has an IC50 of 60 mg/L in the Allium root growth inhibition test .
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- HY-N7374
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Endogenous Metabolite
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Infection
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Cyperine is a phytotoxic fungal metabolite that has been found in A. cypericola. It inhibits A. thaliana enoyl-acyl carrier protein reductase (ENR; IC50=89 μM). Cyperine induces necrosis in a panel of nine plant species in a leaf bioassay and inhibits root growth in A. thaliana seedlings (IC50=38.4 μM).
|
-
- HY-N4014
-
|
|
Others
|
Others
|
|
Ilicol is a natural product isolated from the roots of Saussurea lappa Clarke. Ilicol inhibits root growth and shows IC50 values of 1.22, 2.90, 7.35, 8.07 mM against P. miliaceum , A. sativa, L. sativa , and R. sativus, respectively. Ilicol reduces Allium cepa cell division without chromosome aberration .
|
-
- HY-W001940S
-
|
|
Isotope-Labeled Compounds
Amino Acid Derivatives
Bacterial
|
Infection
Cardiovascular Disease
|
|
DL-m-Tyrosine-d3 is the deuterium labeled DL-m-Tyrosine (HY-W001940). DL-m-Tyrosine is a non-protein amino acid. DL-m-Tyrosine inhibits microbial growth and spore formation. DL-m-Tyrosine also inhibits root growth in various plants, such as lettuce and Arabidopsis. DL-m-Tyrosine, when used in combination with Carbidopa (HY-B0311), has a potent antihypertensive effect. DL-m-Tyrosine can be used in research on biopesticide design.
|
-
- HY-N1458R
-
|
|
Reference Standards
Parasite
Autophagy
p62
Reactive Oxygen Species (ROS)
|
Infection
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Isoschaftoside (Standard) is the analytical standard of Isoschaftoside. This product is intended for research and analytical applications. Isoschaftoside, a C-glycosylflavonoid from Desmodium uncinatum root exudate, can inhibit growth of germinated S. hermonthica radicles. Isoschaftoside reduces reactive oxygen species (ROS) and induces proliferation in senescent cells. Isoschaftoside activates autophagy. Isoschaftoside can be used for anti-tumor, anti-inflammatory, antioxidant, antihypertensive, hepatoprotective and nematicidal study.
|
-
- HY-119609
-
|
|
Bacterial
Cholinesterase (ChE)
β-glucuronidase
|
Infection
|
|
Ilicicolin C exhibits antibacterial activity against Pseudomonas syringae with IC50 of 28.5 µg/mL. Ilicicolin C exhibits weak inhibitory activities against acetylcholinesterase (AChE) and β-glucuronidase with IC50 of 30-43 µg/mL. Ilicicolin C exhibits weak cytoxicity in human lung fibroblasts with IC50 of 64-120 µg/mL. Ilicicolin C affects seed germination and root tip growth of lettuce .
|
-
- HY-N1381R
-
|
|
Reference Standards
Apoptosis
|
Inflammation/Immunology
Cancer
|
|
Periplocin (Standard) is the analytical standard of Periplocin. This product is intended for research and analytical applications. Periplocin is a cardiotonic steroid isolated from root-bark Periploca sepium Bunge. Periplocin promotes tumor cell apoptosis and inhibits tumor growth. Periplocin has the potential to facilitate wound healing through the activation of Src/ERK and PI3K/Akt pathways mediated by Na/K-ATPase .
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-
- HY-B2050S
-
|
|
Isotope-Labeled Compounds
Microtubule/Tubulin
|
Others
|
|
Trifluralin-d14 is the deuterium labeled Trifluralin. Trifluralin is a selective, preemergence, soil-applied herbicide providing control of many important annual grass and broadleaf weed species. Trifluralin prevents weed growth by inhibiting root development through the interruption of mitosis. Trifluralin binds to tubulin and results in the failure of spindle apparatus and cell plate formation. Trifluralin inhibits radicle development on roots. Trifluralin inhibits cell mitosis. Trifluralin is considered to be neurotoxic and haematotoxic .
|
-
- HY-N2132R
-
|
Flavokavain B (Standard)
|
Reference Standards
Apoptosis
|
Cancer
|
|
Flavokawain B (Standard) is the analytical standard of Flavokawain B. This product is intended for research and analytical applications. Flavokawain B (Flavokavain B) is a chalcone isolated from the root extracts of kava-kava plant and a potent apoptosis inducer for inhibiting the growth of various cancer cell lines. Flavokawain B (Flavokavain B) shows strong antiangiogenic activity. Flavokawain B (Flavokavain B) inhibits human brain endothelial cell (HUVEC) migration and tube formation with very low and non-toxic concentrations .
|
-
- HY-B2050R
-
|
|
Reference Standards
Microtubule/Tubulin
Herbicide
|
Others
|
|
Trifluralin (Standard) is the analytical standard of Trifluralin. This product is intended for research and analytical applications. Trifluralin is a selective, preemergence, soil-applied herbicide providing control of many important annual grass and broadleaf weed species. Trifluralin prevents weed growth by inhibiting root development through the interruption of mitosis. Trifluralin binds to tubulin and results in the failure of spindle apparatus and cell plate formation. Trifluralin inhibits radicle development on roots. Trifluralin inhibits cell mitosis. Trifluralin is considered to be neurotoxic and haematotoxic .
|
-
- HY-W720629
-
|
|
Isotope-Labeled Compounds
Phytohormone
Aldehyde Dehydrogenase (ALDH)
|
Others
|
|
Cyanamide- 15N2 is the 15N-labeled Cyanamide (HY-Y0070). Cyanamide is a cell division and plant growth inhibitor, as well as an allelochemical derived from Vicia villosa. Cyanamide inhibits root growth and biomass accumulation in a dose-dependent manner by disrupting the formation of mitotic spindles and phragmoplast complexes, reducing the number of mitotic cells and blocking the cell cycle. The effects of Cyanamide are partially reversible after removal from low-concentration environments. Cyanamide is also a specific inhibitor of aldehyde dehydrogenase (ALDH). Although Cyanamide has no direct effect on tumor growth, it can significantly enhance the anti-tumor efficacy of Cyclophosphamide (HY-17420) at non-toxic doses by inhibiting the inactivation of Cyclophosphamide. Cyanamide enables Cyclophosphamide to exert equivalent therapeutic effects at lower doses, effectively inhibiting the growth of primary and metastatic tumors and prolonging the lifespan of tumor-bearing mice. Cyanamide is commonly used in studies related to ha-1 hepatoma and rls lymphosarcoma .
|
-
- HY-N0373R
-
|
|
Reference Standards
Amyloid-β
Apoptosis
NOD-like Receptor (NLR)
|
Neurological Disease
|
|
Licochalcone B (Standard) is the analytical standard of Licochalcone B. This product is intended for research and analytical applications. Licochalcone B is an extract from the root of Glycyrrhiza uralensis. Licochalcone B inhibits amyloid β (42) self-aggregation (IC50=2.16 μM) and disaggregate pre-formed Aβ42 fibrils, reduce metal-induced Aβ42 aggregation through chelating metal ionsLicochalcone B inhibits phosphorylation of NF-κB p65 in LPS signaling pathway. Licochalcone B inhibits growth and induces apoptosis of NSCLC cells. Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7‐NLRP3 interaction .
|
-
- HY-W001940R
-
|
|
Amino Acid Derivatives
Reference Standards
Bacterial
|
Infection
Cardiovascular Disease
|
|
DL-m-Tyrosine (Standard) is the analytical standard of DL-m-Tyrosine (HY-W001940). This product is intended for research and analytical applications. DL-m-Tyrosine is a non-protein amino acid. DL-m-Tyrosine inhibits microbial growth and spore formation. DL-m-Tyrosine also inhibits root growth in various plants, such as lettuce and Arabidopsis. DL-m-Tyrosine, when used in combination with Carbidopa (HY-B0311), has a potent antihypertensive effect. DL-m-Tyrosine can be used in research on biopesticide design .
|
-
- HY-W097168
-
|
N-Cbz-DL-histidine
|
Amino Acid Derivatives
|
Others
|
|
Z-DL-His-OH (N-Cbz-DL-histidine) (Compound 14) is a Histidine derivative. Z-DL-His-OH shows no inhibitory effect on the root growth of rapeseed .
|
-
- HY-N11950
-
|
|
Others
|
Others
|
|
N-Vanillyloctanamide is a capsaicinoid that has the activity of inhibiting the root growth of plant seedlings. N-Vanillyloctanamide significantly reduces the root length of Lactuca sativa (seedling) in a dose-dependent manner .
|
-
- HY-N13921
-
|
|
Drug Derivative
|
Others
|
|
Aphidicolin-3,18-orthoacetate is an aphidicolin derivative that inhibits the root growth of rice seedlings .
|
-
- HY-116690R
-
|
|
Herbicide
Reference Standards
|
Others
|
|
Daimuron (Standard) is the analytical standard of Daimuron. This product is intended for research and analytical applications. Daimuron is a herbicide safener. Daimuron has a protective effect against the inhibition of seed root elongation by chloroacetanilide herbicides .
|
-
- HY-116690
-
|
|
Herbicide
|
Others
|
|
Daimuron is a herbicide safener. Daimuron has a protective effect against the inhibition of seed root elongation by chloroacetanilide herbicides .
|
-
- HY-N19220
-
|
|
Bacterial
Endogenous Metabolite
Antibiotic
|
Infection
Cancer
|
|
Radiclonic acid acts as an antibacterial agent, anticancer agent, and root growth promoter. Radiclonic acid is isolable from fungi of the genus Penicillium. Radiclonic acid exhibits antibacterial activity against MRSA with a MIC of 3.13 μg/mL. Radiclonic acid shows anticancer activity against esophageal cancer, bladder cancer, and liver cancer. Radiclonic acid promotes root growth in Chinese cabbage seedlings. Radiclonic acid is inactive against pancreatic cancer and cervical cancer. Radiclonic acid can be used in research related to Staphylococcus aureus infection, bladder cancer, esophageal cancer, and liver cancer .
|
-
- HY-N15426
-
|
|
Herbicide
|
Others
|
|
Herbicidal Agent 9 (Compound 5) is a herbicidal derivative of 23-spirocholestane. In combination with Compound 6, Herbicidal Agent 9 inhibits Arabidopsis root growth, exhibiting an EC50 of 6.89 μM .
|
-
- HY-168786
-
|
|
Herbicide
|
Others
|
|
4,6,4'-Trihydroxy-3'-methoxyaurone is an herbicide. At concentrations of 100 and 1000 µg/mL, 4,6,4'-Trihydroxy-3'-methoxyaurone is able to inhibit the growth of rape root and barnyardgrass seedlings 1.
|
-
- HY-170401
-
|
|
Bacterial
Herbicide
|
Infection
|
|
Antibacterial agent 260 (Compound 4r) exhibits board-spectrum antibacterial activity, inhibits P. aeruginosa and S. aureus with MIC of 0.0076 μM. Antibacterial agent 260 acts as a herbicidal agent, that inhibits the root- and stem-growth of Raphanus sativus L. (radish seed) .
|
-
- HY-N13800
-
|
|
Phytohormone
|
Infection
Cancer
|
|
3-O-Debenzoylzeylenone is a polyoxygenated cyclohexene plant growth hormone that exists in the leaves of Uvaria purpurea and the aerial parts of Uvaria grandiflora. 3-O-Debenzoylzeylenone is an auxin analog that inhibits root growth and promotes shoot growth of Lactuca sativa seedlings. 3-O-Debenzoylzeylenone exhibits cytotoxicity against various cancer cells and can be used in studies related to lung cancer, melanoma, epidermoid carcinoma, liver cancer, gastric cancer, colon adenocarcinoma, acute leukemia, breast cancer, and prostate cancer .
|
-
- HY-N0186S3
-
|
Indolebutyric acid-d2
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Indole-3-butyric acid-d2 (Indolebutyric acid-d2) is the deuterium labeled Indole-3-butyric acid (HY-N0186). Indole-3-butyric acid (3-indolebutyric acid) is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate. Indole 3-butyric acid is an auxin precursor, and is converted to indole 3-acetic acid (IAA) in a peroxisomal β-oxidation process .
|
-
- HY-N15007
-
|
|
Drug Derivative
|
Others
|
|
6-Ethoxyethyl-5-hydroxy-2,7-dime-thoxy-1,4-naphtoquinone is a naphthoquinone compound that causes branch wilt in larch and inhibits seed germination and growth in lettuce. 6-Ethoxyethyl-5-hydroxy-2,7-dime-thoxy-1,4-naphtoquinone completely inhibits hypocotyl and root growth at 100 ppm and more than 95% at 50 ppm .
|
-
- HY-182408
-
|
|
Glycosyltransferase
|
Others
|
|
Endosidin7 is a specific inhibitor for plant callose deposition during cytokinesis. Endosidin7 inhibits cytokinesis-specific callose deposition at the cell plate, disrupts cell plate maturation, and alters localization of cell plate-associated proteins during late cell plate development. Endosidin7 slows root growth and induces formation of cell wall stubs in Arabidopsis thaliana seedlings .
|
-
- HY-W721611
-
|
|
Herbicide
|
Others
|
|
Terbucarb is a phenylcarbamate herbicide. Terbucarb disrupts the mitotic microtubule organizing centers in plant cells, leading to the formation of multipolar spindles and branched phragmoplasts, thereby inhibiting plant growth. An "anaphase star" pattern induced by Terbucarb is observed in onion root tips. Terbucarb is cytotoxic to isolated rat hepatocytes, inducing cell death accompanied by depletion of intracellular ATP, protein thiols and glutathione .
|
-
- HY-W725041
-
|
|
Herbicide
|
Others
|
|
Methiozolin is an oxazoline herbicide designed for the selective control of annual bluegrass in turfgrass. Methiozolin strongly inhibits the biosynthesis of cellulose and hemicellulose in corn root cells at low concentrations. Methiozolin inhibits recombinant Arabidopsis thaliana tyrosine aminotransferase, with a IC50 of approximately 200 µM. Methiozolin not only effectively controls vegetative growth but also significantly suppresses inflorescence formation, which helps reduce the seed bank .
|
-
- HY-P11783
-
|
|
Fungal
|
Infection
|
|
Surfactin C2 is a lipopeptide produced by Bacillus subtilis A18 with antifungal activity. Surfactin C2 acts against Heterobasidion annosum and Heterobasidion parviporum. Surfactin C2 exerts its activity mainly through membrane‑active effects to disrupt fungal cell structures and inhibit mycelial growth. Surfactin C2 can be used for the research of butt rot and root rot of conifers .
|
-
- HY-N17336
-
-
- HY-Y0070
-
|
|
Phytohormone
Aldehyde Dehydrogenase (ALDH)
|
Cancer
|
|
Cyanamide is a cell division and plant growth inhibitor, as well as an allelochemical derived from Vicia villosa. Cyanamide inhibits root growth and biomass accumulation in a dose-dependent manner by disrupting the formation of mitotic spindles and phragmoplast complexes, reducing the number of mitotic cells and blocking the cell cycle. The effects of Cyanamide are partially reversible after removal from low-concentration environments. Cyanamide is also a specific inhibitor of aldehyde dehydrogenase (ALDH). Although Cyanamide has no direct effect on tumor growth, it can significantly enhance the anti-tumor efficacy of Cyclophosphamide (HY-17420) at non-toxic doses by inhibiting the inactivation of Cyclophosphamide. Cyanamide enables Cyclophosphamide to exert equivalent therapeutic effects at lower doses, effectively inhibiting the growth of primary and metastatic tumors and prolonging the lifespan of tumor-bearing mice. Cyanamide is commonly used in studies related to ha-1 hepatoma and rls lymphosarcoma .
|
-
- HY-125778
-
|
|
Others
|
Metabolic Disease
|
|
Cochlioquinone is a sesquiterpene metabolite originally isolated from C. miyabeanus. It is a phytotoxin that inhibits root growth of finger millet (E. coracana) and rice plants (O. sativa) by 59.9 and 51.7%, respectively, when used at a concentration of 100 ppm.2 Cochlioquinone B inhibits NADH oxidase and NADH-2,3-dimethoxy-5-pentyl-1,4-benzoquinone reductase from bovine heart mitochondria.
|
-
- HY-179025
-
|
|
Phytohormone
|
Others
|
|
GA3ox-IN-1 (Compound 10e) is a GA3β-hydroxylase (GA3ox) inhibitor. GA3ox-IN-1 inhibits Arabidopsis root growth with an IC50 of 90 μM. GA3ox-IN-1 also suppresses the elongation of rice second leaf sheath. GA3ox-IN-1 can alleviate oxidative damage to Arabidopsis seedlings under NaCl salt stress and reduce the accumulation of superoxide anion .
|
-
- HY-N1964B
-
|
GA3 Sterile Solution (1 mg/ml)
|
Drug Derivative
|
Metabolic Disease
|
|
Gibberellic acid Sterile Solution (1 mg/mL) (GA3 Sterile Solution (1 mg/mL)) is a natural plant growth regulator with oral bioactivity. Gibberellic acid Sterile Solution (1 mg/mL) governs multiple plant developmental events, including seed germination, cell elongation, floral organ formation, and rice spikelet fertility. Gibberellic acid Sterile Solution (1 mg/mL) optimizes root morphology and secondary metabolite production in Echinacea purpurea hairy roots, and serves as a bioactive seed priming agent to improve chilling stress tolerance in chickpea. Gibberellic acid Sterile Solution (1 mg/mL) mediates modulation of enzyme activity and secondary metabolism in plants and exerts tissue-specific regulatory effects on antioxidant systems and lipid peroxidation in rats. Gibberellic acid Sterile Solution (1 mg/mL) can be used in studies of plant growth, metabolism, and abiotic stress responses .
|
-
- HY-N12990
-
|
MyA
|
Herbicide
Fungal
|
Others
|
|
Myrigalone A (MyA) is a plant ethylene biosynthesis inhibitor and natural herbicide . Myrigalone A possesses antioxidant, antifungal, and antimicrobial activities. Myrigalone A interferes with auxin homeostasis during seed germination. Myrigalone A delays seed germination, inhibits the formation of roots, hypocotyls, and root hairs, and causes developmental delay in specific organisms. Myrigalone A triggers the induction of detoxification programs, alters the metabolism of gibberellins, cis-(+)-12-oxophytodienoic acid, and jasmonic acid, disrupts the antioxidant system and oxidative signaling, and impairs the function of aquaporins and water uptake in imbibed seeds. Myrigalone A can be used in studies related to herbicides and plant growth regulators .
|
-
- HY-167959
-
|
|
Herbicide
|
Infection
|
|
MCPA-isooctyl is a selective conductive phenoxycarboxylate herbicide and an alternative to 2,4-D Butyl ester (HY-B0867). MCPA-isooctyl effectively controls broadleaf weeds in various crop fields via post-emergence foliar or soil treatment. MCPA-isooctyl is absorbed by the roots, stems and leaves of plants; it is easily metabolized and detoxified in gramineous crops, but difficult to metabolize in dicotyledonous weeds, causing stem and leaf distortion, root deformation, and eventually weed death. When formulated into chitosan nanoparticles, MCPA-isooctyl still significantly inhibits the growth of weeds in wheat fields, and reduces their chlorophyll content and biomass at low doses .
|
-
- HY-N18080
-
|
|
Parasite
DNA Alkylator/Crosslinker
Bacterial
|
Infection
Inflammation/Immunology
Cancer
|
|
Parthenin is a pseudoguaianolide-type sesquiterpene lactone present in Parthenium hysterophorus L. Parthenin induces chromosomal aberrations, mainly chromatid breaks, in human peripheral blood lymphocytes. Parthenin exhibits toxicity against Salmonella typhimurium and Escherichia coli strains, with reduced toxicity in the presence of a metabolic activation system (S9). Parthenin acts as an antifeedant against the 6th instar larvae of the tobacco cutworm (Spodoptera litura). Parthenin shows insecticidal activity against adult cowpea weevils (Callosobruchus maculatus). Parthenin inhibits seed germination and seedling growth of sicklepod (Cassia tora). Parthenin possesses nematicidal activity against the 2nd instar larvae of the southern root-knot nematode (Meloidogyne incognita). Parthenin serves as a research agent for studies related to cancer, malaria, amoebiasis, inflammatory diseases, and bacterial infections .
|
-
- HY-P991947
-
|
AFS98; TG3003
|
c-Fms
|
Inflammation/Immunology
|
|
ELB041 (AFS98) is a rat monoclonal anti-murine c-fms antibody (IgG2a). AFS98 inhibits M-CSF–dependent colony formation and cell growth by blocking the binding of M-CSF to its receptor. AFS98 prevents development of fatty streaks in ApoE-deficient mice. ELB041 can be used for the research of atherosclerosis .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-N0186
-
|
Indolebutyric acid
|
Biochemical Assay Reagents
|
|
Indole-3-butyric acid (3-indolebutyric acid) is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate. Indole 3-butyric acid is an auxin precursor, and is converted to indole 3-acetic acid (IAA) in a peroxisomal β-oxidation process .
|
-
- HY-W116336D
-
|
|
Biochemical Assay Reagents
|
|
Zinc oxide, <100 nm particle size is a nitrate reductase modulator and growth promoter with plant stress resistance activity and oral toxicity. Zinc oxide, <100 nm particle size acts as a nutrient source for maize plants. By enhancing nitrate reductase activity and reducing free proline levels, it significantly improves plant height, root length and dry matter weight of maize, and its growth-promoting effect is comparable to that of traditional zinc sulfate fertilizer. Zinc oxide, <100 nm particle size induces anemia-related and persistent tissue inflammatory damage, leading to obvious histopathological adverse reactions in the stomach, pancreas, eyes and prostate of rats. Zinc oxide, <100 nm particle size acts as a non-toxic antibacterial agent and selective cytotoxin against multiple bacteria, fungi and spores .
|
-
- HY-18570B
-
|
NAA
|
Biochemical Assay Reagents
|
|
1-Naphthaleneacetic acid,suitable for plant cell culture (NAA) is a plant growth hormone. 1-Naphthaleneacetic acid,suitable for plant cell culture promotes plant growth and induces root cluster formation. Naphthaleneacetic acid,suitable for plant cell culture is applicable for plant cell culture .
|
-
- HY-N0186R
-
|
Indolebutyric acid (Standard)
|
Biochemical Assay Reagents
|
|
Indole-3-butyric acid (Standard) is the analytical standard of Indole-3-butyric acid. This product is intended for research and analytical applications. Indole-3-butyric acid (3-indolebutyric acid) is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate. Indole 3-butyric acid is an auxin precursor, and is converted to indole 3-acetic acid (IAA) in a peroxisomal β-oxidation process .
|
-
- HY-W054259
-
|
N,N'-Difurfuryloxamide; N1,N2-Bis(furan-2-ylmethyl)oxalamide
|
Biochemical Assay Reagents
|
|
BFMO (N,N'-Difurfuryloxamide) is an oxamide derivative and a bidentate ligand. BFMO exhibits plant growth regulatory activity and root growth inhibitory activity. BFMO can promote the copper-catalyzed N-arylation reaction between aniline compounds and cyclic secondary amines, realizing the coupling of (hetero) aryl bromides with (hetero) aryl amines and cyclic secondary amines .
|
-
- HY-N0186B
-
|
IBA
|
Biochemical Assay Reagents
|
|
Indole-3-butyric acid,suitable for plant cell culture (IBA) is a plant auxin and a good rooting agent. Indole-3-butyric acid,suitable for plant cell culture can promote rooting of herbaceous and woody ornamental plants and is used to increase fruiting rate. Indole-3-butyric acid is an auxin precursor that is converted into indole 3-acetic acid (IAA) during peroxisomal β-oxidation. Indole-3-butyric acid,suitable for plant cell culture can be used for cell culture .
|
-
- HY-N1964A
-
|
|
Biochemical Assay Reagents
|
|
Gibberellic acid, suitable for plant cell culture (GA3, suitable for plant cell culture) is a natural plant growth regulator with oral bioactivity. Gibberellic acid, suitable for plant cell culture governs multiple plant developmental events, including seed germination, cell elongation, floral organ formation, and rice spikelet fertility. Gibberellic acid, suitable for plant cell culture optimizes root morphology and secondary metabolite production in Echinacea purpurea hairy roots, and serves as a bioactive seed priming agent to improve chilling stress tolerance in chickpea. Gibberellic acid, suitable for plant cell culture mediates modulation of enzyme activity and secondary metabolism in plants and exerts tissue-specific regulatory effects on antioxidant systems and lipid peroxidation in rats. Gibberellic acid, suitable for plant cell culture can be used in studies of plant growth, metabolism, and abiotic stress responses .
|
-
- HY-Y0070
-
|
|
Biochemical Assay Reagents
|
|
Cyanamide is a cell division and plant growth inhibitor, as well as an allelochemical derived from Vicia villosa. Cyanamide inhibits root growth and biomass accumulation in a dose-dependent manner by disrupting the formation of mitotic spindles and phragmoplast complexes, reducing the number of mitotic cells and blocking the cell cycle. The effects of Cyanamide are partially reversible after removal from low-concentration environments. Cyanamide is also a specific inhibitor of aldehyde dehydrogenase (ALDH). Although Cyanamide has no direct effect on tumor growth, it can significantly enhance the anti-tumor efficacy of Cyclophosphamide (HY-17420) at non-toxic doses by inhibiting the inactivation of Cyclophosphamide. Cyanamide enables Cyclophosphamide to exert equivalent therapeutic effects at lower doses, effectively inhibiting the growth of primary and metastatic tumors and prolonging the lifespan of tumor-bearing mice. Cyanamide is commonly used in studies related to ha-1 hepatoma and rls lymphosarcoma .
|
-
- HY-N1964B
-
|
GA3 Sterile Solution (1 mg/ml)
|
Biochemical Assay Reagents
|
|
Gibberellic acid Sterile Solution (1 mg/mL) (GA3 Sterile Solution (1 mg/mL)) is a natural plant growth regulator with oral bioactivity. Gibberellic acid Sterile Solution (1 mg/mL) governs multiple plant developmental events, including seed germination, cell elongation, floral organ formation, and rice spikelet fertility. Gibberellic acid Sterile Solution (1 mg/mL) optimizes root morphology and secondary metabolite production in Echinacea purpurea hairy roots, and serves as a bioactive seed priming agent to improve chilling stress tolerance in chickpea. Gibberellic acid Sterile Solution (1 mg/mL) mediates modulation of enzyme activity and secondary metabolism in plants and exerts tissue-specific regulatory effects on antioxidant systems and lipid peroxidation in rats. Gibberellic acid Sterile Solution (1 mg/mL) can be used in studies of plant growth, metabolism, and abiotic stress responses .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P11783
-
|
|
Fungal
|
Infection
|
|
Surfactin C2 is a lipopeptide produced by Bacillus subtilis A18 with antifungal activity. Surfactin C2 acts against Heterobasidion annosum and Heterobasidion parviporum. Surfactin C2 exerts its activity mainly through membrane‑active effects to disrupt fungal cell structures and inhibit mycelial growth. Surfactin C2 can be used for the research of butt rot and root rot of conifers .
|
| Cat. No. |
Product Name |
Target |
Research Area |
Image |
-
- HY-P991947
-
|
AFS98; TG3003
|
c-Fms
|
Inflammation/Immunology
|
|
ELB041 (AFS98) is a rat monoclonal anti-murine c-fms antibody (IgG2a). AFS98 inhibits M-CSF–dependent colony formation and cell growth by blocking the binding of M-CSF to its receptor. AFS98 prevents development of fatty streaks in ApoE-deficient mice. ELB041 can be used for the research of atherosclerosis .
|
-
(5)
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N1964
-
-
-
- HY-N0186
-
-
-
- HY-N1381
-
-
-
- HY-N0373
-
Licochalcone B
Maximum Cited Publications
12 Publications Verification
|
Chalcones
Flavonoids
Leguminosae
Plants
Glycyrrhiza uralensis Fisch.
Source Classification
|
Amyloid-β
Apoptosis
NOD-like Receptor (NLR)
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Licochalcone B is an extract from the root of Glycyrrhiza uralensis. Licochalcone B inhibits amyloid β (42) self-aggregation (IC50=2.16 μM) and disaggregate pre-formed Aβ42 fibrils, reduce metal-induced Aβ42 aggregation through chelating metal ionsLicochalcone B inhibits phosphorylation of NF-κB p65 in LPS signaling pathway. Licochalcone B inhibits growth and induces apoptosis of NSCLC cells. Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7‐NLRP3 interaction .
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- HY-N1458
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- HY-136409
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C10-HSL
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Microorganisms
Source Classification
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Bacterial
Reactive Oxygen Species (ROS)
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N-decanoyl-L-homoserine lactone (C10-HSL) is a N-acyl-homoserine lactone (AHL) N-decanoyl-L-homoserine lactone can inhibit primary root growth in Arabidopsis. N-decanoyl-L-homoserine lactone triggers a transient and immediate increase in the concentrations of cytosolic free Ca 2+ and reactive oxygen species (ROS), increases the activity of mitogen-activated protein kinase 6 (MPK6), and induces nitric oxide (NO) production in Arabidopsis roots .
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- HY-N9599
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- HY-B1918
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- HY-101404
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- HY-W016289
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- HY-N6924
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Infection
Structural Classification
Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow
Classification of Application Fields
Panax japonicas C. A. Mey.
Metabolic Disease
Plants
Disease Research Fields
Saccharides
Araliaceae
Source Classification
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HIV
PIN1
Fungal
GLUT
Reactive Oxygen Species (ROS)
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Zingibroside R1 is an orally active triterpene saponin with multiple biological activities including antioxidant, anti-inflammatory, antiviral, and metabolic regulatory properties. Zingibroside R1 reduces the expression of PIN family members, inhibits the expression of PLT1/PLT2, WOX5, SHR, and SCR, disrupts auxin transport and distribution, triggers plant ROS responses, and inhibits root growth. Zingibroside R1 extends the lifespan of Caenorhabditis elegans, enhances its heat stress resistance, and improves its motor ability. Hydrogel derivatives of Zingibroside R1 inhibit the proliferation of Candida albicans by binding to its β-1,3-glucan and exhibit antifungal activity. Zingibroside R1 inhibits GLUT1-mediated uptake and alleviates liver injury. Zingibroside R1 can be used in research related to neurodegenerative diseases, vulvovaginal candidiasis, acute liver injury, Ehrlich ascites tumor and HIV-1 infection .
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- HY-W001940
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- HY-N0186R
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- HY-N7659
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Structural Classification
Isatis tinctoria L.
Glucosinolates
Plants
Brassicaceae
Source Classification
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Phytohormone
Apoptosis
Microtubule/Tubulin
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Glucobrassicin is an indole-based anticancer agent and plant growth-regulating hormone. Glucobrassicin exerts its biological activity by disrupting the integrity of microtubule networks in both plant and mammalian cells. At high concentrations, Glucobrassicin inhibits seed germination and root growth; it can also specifically induce apoptosis in mammalian cancer cells and interfere with the intercellular transmission of viruses that rely on microtubules. In plants, Glucobrassicin can be catalyzed by myrosinase to release growth-regulating substances, exhibiting a concentration-dependent growth-regulating effect .
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- HY-N1450
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- HY-N1964R
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- HY-101404R
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- HY-125698
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- HY-N15454
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Altertenuol
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Microorganisms
Phenols
Polyphenols
Source Classification
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Herbicide
Bacterial
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Altenuisol is a compound that can be found in the pathogenic fungus of the genus Alternaria in Xanthium italicum. It has herbicidal activity. At a low concentration of Altenuisol (10 μg/mL), it promotes the root growth of Pennisetum alopecuroides and Medicago sativa by 75.2% and 51.0% respectively. At a high concentration of Altenuisol (1000 μg/mL), the inhibition rates of root growth of Pennisetum alopecuroides and Medicago sativa are 52.0% and 42.0% respectively. In addition, Altenuisol is cytotoxic to HeLa cells and also exhibits antibacterial and antioxidant activities. Altenuisol is expected to be used in research in fields such as agricultural weeding, anti - tumor, and anti - infection .
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- HY-N12170
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- HY-N1450R
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- HY-116498
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Microorganisms
Source Classification
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Others
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Penigequinolone A is an alkaloid isolated from Penicillium. It is lethal to P. penetrans (LD50=100 mg/L) but has no effect on C. elegans at concentrations up to 1000 mg/L.1 Penigequinolone A also accelerates the root growth of rice seedlings in a dose-dependent manner.
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- HY-N2021AR
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- HY-N7697BR
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Structural Classification
Microorganisms
Saccharides
Source Classification
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Reference Standards
Others
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Gibberellic acid (Standard) is the analytical standard of Gibberellic acid. This product is intended for research and analytical applications. Gibberellic Acid is named after the fungus Gibberella fujikuroi. Gibberellic Acid regulates processes in plant development and growth, including seed development and germination, stem and root growth, cell division, and flowering time. Gibberellic Acid also improves plant response to growth stress caused by various environmental stresses, such as cold stress, drought stress, heavy metal stress, etc. Gibberellic Acid also causes increased lipid peroxidation and fluctuations in the antioxidant defense system in rats .
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- HY-N4014
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- HY-N1458R
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- HY-119609
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- HY-N1381R
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- HY-N2132R
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Flavokavain B (Standard)
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Structural Classification
Chalcones
Monophenols
Flavonoids
other families
Phenols
Plants
Source Classification
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Reference Standards
Apoptosis
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Flavokawain B (Standard) is the analytical standard of Flavokawain B. This product is intended for research and analytical applications. Flavokawain B (Flavokavain B) is a chalcone isolated from the root extracts of kava-kava plant and a potent apoptosis inducer for inhibiting the growth of various cancer cell lines. Flavokawain B (Flavokavain B) shows strong antiangiogenic activity. Flavokawain B (Flavokavain B) inhibits human brain endothelial cell (HUVEC) migration and tube formation with very low and non-toxic concentrations .
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- HY-N0373R
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- HY-W001940R
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- HY-N11950
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- HY-N13921
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- HY-N19220
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Structural Classification
Microorganisms
Lipid
Source Classification
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Bacterial
Endogenous Metabolite
Antibiotic
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Radiclonic acid acts as an antibacterial agent, anticancer agent, and root growth promoter. Radiclonic acid is isolable from fungi of the genus Penicillium. Radiclonic acid exhibits antibacterial activity against MRSA with a MIC of 3.13 μg/mL. Radiclonic acid shows anticancer activity against esophageal cancer, bladder cancer, and liver cancer. Radiclonic acid promotes root growth in Chinese cabbage seedlings. Radiclonic acid is inactive against pancreatic cancer and cervical cancer. Radiclonic acid can be used in research related to Staphylococcus aureus infection, bladder cancer, esophageal cancer, and liver cancer .
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- HY-N15426
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- HY-N13800
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Structural Classification
Uvaria grandiflora Roxb.
Other Phenylpropanoids
Phenylpropanoids
Plants
Annonaceae
Source Classification
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Phytohormone
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3-O-Debenzoylzeylenone is a polyoxygenated cyclohexene plant growth hormone that exists in the leaves of Uvaria purpurea and the aerial parts of Uvaria grandiflora. 3-O-Debenzoylzeylenone is an auxin analog that inhibits root growth and promotes shoot growth of Lactuca sativa seedlings. 3-O-Debenzoylzeylenone exhibits cytotoxicity against various cancer cells and can be used in studies related to lung cancer, melanoma, epidermoid carcinoma, liver cancer, gastric cancer, colon adenocarcinoma, acute leukemia, breast cancer, and prostate cancer .
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- HY-N17336
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- HY-125778
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Human Gut Microbiota Metabolites
Microorganisms
Endogenous metabolite
Source Classification
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Others
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Cochlioquinone is a sesquiterpene metabolite originally isolated from C. miyabeanus. It is a phytotoxin that inhibits root growth of finger millet (E. coracana) and rice plants (O. sativa) by 59.9 and 51.7%, respectively, when used at a concentration of 100 ppm.2 Cochlioquinone B inhibits NADH oxidase and NADH-2,3-dimethoxy-5-pentyl-1,4-benzoquinone reductase from bovine heart mitochondria.
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- HY-N12990
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MyA
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Structural Classification
Flavonoids
Ketones, Aldehydes, Acids
Plants
Dihydrochalcones
Myrica gale L.
Source Classification
Myricaceae
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Herbicide
Fungal
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Myrigalone A (MyA) is a plant ethylene biosynthesis inhibitor and natural herbicide . Myrigalone A possesses antioxidant, antifungal, and antimicrobial activities. Myrigalone A interferes with auxin homeostasis during seed germination. Myrigalone A delays seed germination, inhibits the formation of roots, hypocotyls, and root hairs, and causes developmental delay in specific organisms. Myrigalone A triggers the induction of detoxification programs, alters the metabolism of gibberellins, cis-(+)-12-oxophytodienoic acid, and jasmonic acid, disrupts the antioxidant system and oxidative signaling, and impairs the function of aquaporins and water uptake in imbibed seeds. Myrigalone A can be used in studies related to herbicides and plant growth regulators .
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- HY-N18080
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Structural Classification
Terpenoids
Sesquiterpenes
Antheroporum pierrei Gagnep.
Plants
Compositae
Source Classification
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Parasite
DNA Alkylator/Crosslinker
Bacterial
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Parthenin is a pseudoguaianolide-type sesquiterpene lactone present in Parthenium hysterophorus L. Parthenin induces chromosomal aberrations, mainly chromatid breaks, in human peripheral blood lymphocytes. Parthenin exhibits toxicity against Salmonella typhimurium and Escherichia coli strains, with reduced toxicity in the presence of a metabolic activation system (S9). Parthenin acts as an antifeedant against the 6th instar larvae of the tobacco cutworm (Spodoptera litura). Parthenin shows insecticidal activity against adult cowpea weevils (Callosobruchus maculatus). Parthenin inhibits seed germination and seedling growth of sicklepod (Cassia tora). Parthenin possesses nematicidal activity against the 2nd instar larvae of the southern root-knot nematode (Meloidogyne incognita). Parthenin serves as a research agent for studies related to cancer, malaria, amoebiasis, inflammatory diseases, and bacterial infections .
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| Cat. No. |
Product Name |
Chemical Structure |
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- HY-101404S
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DL-Homocysteine thiolactone-d4 hydrochloride is the deuterium labeled DL-Homocysteine thiolactone (hydrochloride). DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.
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- HY-122984S
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Diquat-d4 (dibromide) is the deuterium labeled Diquat dibromide (HY-122984) . Diquat dibromide is a comprehensive herbicide commonly used in the cultivation of cotton, soybeans, and other crops to combat unwanted weeds. Diquat dibromide has an IC50 of 60 mg/L in the Allium root growth inhibition test .
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- HY-W001940S
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DL-m-Tyrosine-d3 is the deuterium labeled DL-m-Tyrosine (HY-W001940). DL-m-Tyrosine is a non-protein amino acid. DL-m-Tyrosine inhibits microbial growth and spore formation. DL-m-Tyrosine also inhibits root growth in various plants, such as lettuce and Arabidopsis. DL-m-Tyrosine, when used in combination with Carbidopa (HY-B0311), has a potent antihypertensive effect. DL-m-Tyrosine can be used in research on biopesticide design.
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- HY-B2050S
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Trifluralin-d14 is the deuterium labeled Trifluralin. Trifluralin is a selective, preemergence, soil-applied herbicide providing control of many important annual grass and broadleaf weed species. Trifluralin prevents weed growth by inhibiting root development through the interruption of mitosis. Trifluralin binds to tubulin and results in the failure of spindle apparatus and cell plate formation. Trifluralin inhibits radicle development on roots. Trifluralin inhibits cell mitosis. Trifluralin is considered to be neurotoxic and haematotoxic .
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- HY-W720629
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Cyanamide- 15N2 is the 15N-labeled Cyanamide (HY-Y0070). Cyanamide is a cell division and plant growth inhibitor, as well as an allelochemical derived from Vicia villosa. Cyanamide inhibits root growth and biomass accumulation in a dose-dependent manner by disrupting the formation of mitotic spindles and phragmoplast complexes, reducing the number of mitotic cells and blocking the cell cycle. The effects of Cyanamide are partially reversible after removal from low-concentration environments. Cyanamide is also a specific inhibitor of aldehyde dehydrogenase (ALDH). Although Cyanamide has no direct effect on tumor growth, it can significantly enhance the anti-tumor efficacy of Cyclophosphamide (HY-17420) at non-toxic doses by inhibiting the inactivation of Cyclophosphamide. Cyanamide enables Cyclophosphamide to exert equivalent therapeutic effects at lower doses, effectively inhibiting the growth of primary and metastatic tumors and prolonging the lifespan of tumor-bearing mice. Cyanamide is commonly used in studies related to ha-1 hepatoma and rls lymphosarcoma .
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- HY-N0186S3
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Indole-3-butyric acid-d2 (Indolebutyric acid-d2) is the deuterium labeled Indole-3-butyric acid (HY-N0186). Indole-3-butyric acid (3-indolebutyric acid) is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate. Indole 3-butyric acid is an auxin precursor, and is converted to indole 3-acetic acid (IAA) in a peroxisomal β-oxidation process .
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