1 Result for "

S448

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "S448" in MCE Product Catalog:

Cat. No.: HY-123864
CAS No.: 188804-07-1
Synonyms: S 448
Target:  

Integrin

Research Areas:  

Cardiovascular Disease Cancer

SC-68448 (S 448) is a selective αvβ3 antagonist (IC50 = 1 nM). SC-68448 inhibits αvβ3-mediated endothelial cell proliferation. SC-68448 reduces the total level of αvβ6 in NHBE cells. SC-68448 inhibits angiogenesis in a rat corneal neoplasia model. SC-68448 inhibits tumor growth and completely prevents the development of hypercalcemia in a rat Ledich cell tumor model. SC-68448 can be used in research on cardiovascular and cerebrovascular diseases such as hypercalcemia and cancers such as testicular interstitial cell tumors .
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