2 Results for "

SC 75741

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "SC 75741" in MCE Product Catalog:

36
36 Cited Publications
Cat. No.: HY-10496
CAS No.: 913822-46-5
Purity:  99.24%
Target:  

NF-κB Influenza Virus

Research Areas:  

Infection Cancer

SC75741 is a broad and efficient NF-κB inhibitor with an IC50 of 200 nM for p65 . SC75741 blocks influenza viruses (IV) replication. SC75741 impairs DNA binding of the NF-κB subunit p65, resulting in reduced expression of cytokines, chemokines, and pro-apoptotic factors. SC75741 subsequently inhibits caspase activation and blocks caspase-mediated nuclear export of viral ribonucleoproteins .
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Cat. No.: HY-10496R
CAS No.: 913822-46-5
Research Areas:  

Infection Cancer

SC75741 (Standard) is the analytical standard of SC75741 (HY-10496). This product is intended for research and analytical applications. SC75741 is a broad and efficient NF-κB inhibitor with an IC50 of 200 nM for p65 . SC75741 blocks influenza viruses (IV) replication. SC75741 impairs DNA binding of the NF-κB subunit p65, resulting in reduced expression of cytokines, chemokines, and pro-apoptotic factors. SC75741 subsequently inhibits caspase activation and blocks caspase-mediated nuclear export of viral ribonucleoproteins .
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