1 Result for "

SGI 7079

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SGI 7079" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-12964
CAS No.: 1239875-86-5
Purity:  99.32%
Target:  

TAM Receptor

연구분야:  

Cancer

SGI-7079 is a selective, ATP-competitive, orally active inhibitor of the receptor tyrosine kinase Axl. SGI-7079 blocks Axl-mediated signaling pathways such as NF-κB activation and MMP-9 expression, thereby inhibiting tumor cell proliferation, migration and invasion. SGI-7079 is mainly used in the research of malignant tumors such as inflammatory breast cancer and bladder cancer, as well as in combination with immunization (used in combination with PD-1 therapy)[1][2][3].
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