1 Result for "

SM8849

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SM8849" in MCE Product Catalog:

Referencia número: HY-165564
No. CAS: 113759-19-6
Target:  

Drug Derivative

Áreas de investigación:  

Inflammation/Immunology

SM-8849 is a thiazole derivative with anti-arthritis activity. SM-8849 specifically targets and inactivates T cells involved in delayed-type hypersensitivity (DTH) reactions, thereby inhibiting the core immunopathological process of arthritis, but has little effect on the humoral immune process such as antibody production. In a mouse arthritis model induced by Type II Collagen (HY-NP003), SM-8849 significantly alleviated clinical symptoms, reduced bone destruction and joint damage. SM-8849 can be used for the study of autoimmune diseases such as rheumatoid arthritis .
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