1 Result for "

SRI31277

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SRI31277" in MCE Product Catalog:

Cat. No.: HY-182611
CAS No.: 1637468-93-9
Target:  

TGF-β Receptor

Research Areas:  

Inflammation/Immunology Cancer

SRI-31277 is a thrombospondin 1 (TSP-1) inhibitor with a human target pIC50 of 8.28 nM and in vivo activity, and exhibits a very short plasma half-life with intravenous administration.SRI-31277 inhibits interaction between TSP-1 and the latency-associated peptide (LAP) of latent TGF-β, blocking TSP-1-mediated TGF-β activation.SRI-31277 can be used for the research of multiple myeloma and fibrotic conditions .
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