3 Results for "

STAD2

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "STAD2" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P2261
CAS No.: 1542100-77-5
Target:  

PKA

Research Areas:  

Infection

STAD 2 is a potent and selective disruptor of PKA-RII, with a Kd of 6.2 nM. STAD 2 disrupts interactions between PKA and AKAP in an isoform-selective manner. STAD 2 displays antimalarial activity through a PKA-independent mechanism [2].
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Cat. No.: HY-P10319
Target:  

PKA

Research Areas:  

Cardiovascular Disease Cancer

RI-STAD-2 is a high-affinity interfering peptide that regulates the subunit RI of protein kinase A (PKA). RI-STAD-2 interferes with the binding of AKAPs and PKA-RI by simulating the interaction between AKAPs' α-helix domain and PKA-RI's dimerization/anchoration (D/D) domain, thereby affecting PKA activity and intracellular localization. RI-STAD-2 can be used to study the role of AKAPs interaction with PKA-RI in pathological processes such as cardiovascular disease and cancer .
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