1 Result for "

Samotolisib

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Samotolisib" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-12513
CAS No.: 1386874-06-1
Purity:  99.27%
Synonyms: LY3023414
Target:  

PI3K DNA-PK mTOR Autophagy

Research Areas:  

Cancer

Samotolisib (LY3023414) potently and selectively inhibits class I PI3K isoforms, DNA-PK, and mTORC1/2 with IC50s of 6.07 nM, 77.6 nM, 38 nM, 23.8 nM, 4.24 nM and 165 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ, DNA-PK and mTOR, respectively. Samotolisib potently inhibits mTORC1/2 at low nanomolar concentrations .
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