Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
28 Results for "
Sialyl Neolactotetraosylceramide
" in MedChemExpress (MCE) Product Catalog:
Products (28)
28 Results for "Sialyl Neolactotetraosylceramide" in MCE Product Catalog:
5
5 Cited Publications
Target:
Research Areas:
3FAx-Neu5Ac (Compound 8), a Sialic acid peracetylated analog, is a sialyltransferase inhibitor. 3FAx-Neu5Ac substantially reduces expression of the sialylated ligand sialyl Lewis X .
2
2 Cited Publications
Cat. No.: HY-160109
Target:
Research Areas:
Ac5GalNTGc is a potent, peracetylated C-2 thioglycolyl-substituted GalNAc analog that efficiently inhibits mucin-type O-glycan biosynthesis. Ac5GalNTGc reduces leukocyte sialyl-Lewis-X expression and inhibits L-/P-selectin mediated rolling under flow, as well as P-selectin dependent leukocyte-platelet adhesion. Ac5GalNTGc exhibits anti-inflammatory activity in a thioglycollate-induced acute peritonitis model. Ac5GalNTGc can be used for studies of O-glycan/mucin biology, inflammation, and related translational research .
1
Category:
Polysaccharides Endogenous metabolite Disease Research Fields Inflammation/Immunology Saccharides
Target:
1
1
Target:
Research Areas:
Sialyl Lewis A (SLeA) sodium is a tumor-associated carbohydrate antigen, also known as carbohydrate antigen 19-9 (CA19-9), that binds to E-selectin (ELAM-1) and selectins to mediate cell-endothelium adhesion. Sialyl Lewis A sodium promotes cancer cell-vascular endothelium adhesion, and its surface presence correlates with increased tumorigenicity and invasiveness in cancer cells. Sialyl Lewis A sodium shows elevated expression in human adenocarcinomas of the colon, pancreas, and stomach, with expression levels linked to tumor progression and poor prognosis in colorectal and gastric carcinomas. Sialyl Lewis A sodium can be used for the research of cancers, such as colon, pancreas, stomach, and squamous lung cancer .
Synonyms: N-Acetyl-D-lactosamine
Category:
Target:
Cat. No.: HY-P4070
CAS No.: 1188379-43-2
Target:
Research Areas:
Cat. No.: HY-N7575
CAS No.: 21973-23-9
Synonyms: LNFP II
Category:
Polysaccharides Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides Cancer
Target:
Cat. No.: HY-W698390
CAS No.: 81693-22-3
Cat. No.: HY-137878
CAS No.: 26112-88-9
Synonyms: PNP-α-NeuNAc
Cat. No.: HY-125475
CAS No.: 927881-99-0
Synonyms: GMI-1070
Target:
Research Areas:
Rivipansel is a small-molecule glycomimetic pan-selectin antagonist with inhibitory activity against E-selectin and P-selectin. Rivipansel binds tightly to the lectin domain of E-selectin, and selectively blocks the recognition of CD62L by E-selectin without affecting the binding of PSGL-1 to E-selectin. Rivipansel functionally inhibits the adhesion of hematopoietic cells to endothelial cells, and is applicable to research related to sickle cell disease .
Synonyms: Neu5Aca2-6GalNAc-a-Ser/Thr
Target:
Research Areas:
STn/sialyl-Tn is a sialic acid associated with breast cancer and its expression is closely related to HER2-pos. STn/sialyl-Tn can be used as a marker to count cells in malignant nipple discharge (PND) .
Cat. No.: HY-E70284
Target:
Research Areas:
Keratanase II,bacillus circulans,expressed in E.coli has transglycosylation activity. Keratanase II,bacillus circulans,expressed in E.coli efficiently catalyzes the transglycosylation of α(2→3)-sialylated 6,6′-di-sulfo-LacNAc with two kinds of glycosyl acceptors, 6-sulfo-Lewis X and 6,6'-di-sulfo-LacNAc derivatives, providing Sialyl sulfo-hexasaccharide and Sialyl sulfo-pentasaccharide .
Cat. No.: HY-W854385
CAS No.: 92448-22-1
Synonyms: SLeA
Target:
Research Areas:
Sialyl Lewis A (SLeA) is a tumor-associated carbohydrate antigen, also known as carbohydrate antigen 19-9 (CA19-9), that binds to E-selectin (ELAM-1) and selectins to mediate cell-endothelium adhesion. Sialyl Lewis A promotes cancer cell-vascular endothelium adhesion, and its surface presence correlates with increased tumorigenicity and invasiveness in cancer cells. Sialyl Lewis A shows elevated expression in human adenocarcinomas of the colon, pancreas, and stomach, with expression levels linked to tumor progression and poor prognosis in colorectal and gastric carcinomas. Sialyl Lewis A can be used for the research of cancers, such as colon, pancreas, stomach, and squamous lung cancer .
Cat. No.: HY-W145535
CAS No.: 127923-85-7
Cat. No.: HY-E70303
CAS No.: 2178088-82-7
Synonyms: FUT6
Target:
Research Areas:
Fucosyltransferase 6 is a fucosyltransferase that mediates the expression of the tetrasaccharide Sialyl-Lewis x (sLex, CD15s) on the surface of leukocytes. sLex participates in E-selectin-mediated leukocyte rolling and is related to the migration of leukocytes out of blood vessels .
Cat. No.: HY-P990632
CAS No.: 2362015-67-4
Synonyms: HuMab-5B1
Target:
Research Areas:
Cat. No.: HY-E70156
Synonyms: FUT7
Cat. No.: HY-P11293
CAS No.: 1309855-53-5
Target:
Research Areas:
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
