84 Results for "

Streptomyces sp

" in MedChemExpress (MCE) Product Catalog:
Products (84)

84 Results for "Streptomyces sp" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-N12257
CAS No.: 27220-57-1
Antimycin A2 is a selective inhibitor of the cytochrome b-c1 complex in the mitochondrial electron transport chain. Antimycin A2 disrupts mitochondrial membrane potential and produces reactive oxygen species (ROS) by inhibiting electron transfer between cytochrome b and c. Antimycin A2 has bactericidal and piscicidal activity, as well as tumor cell growth inhibitory effects, and can induce S-phase cell cycle arrest and apoptosis in HeLa cells. Antimycin A2 is suitable for research of cervical cancer and fisheries management. Antimycin A2 can be naturally isolated from the fermentation products of Streptomyces sp. strains .
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1 Cited Publications
Cat. No.: HY-113542
CAS No.: 100513-53-9
Synonyms: (+)-Blasticidin A
Target:  

Antibiotic Fungal

Research Areas:  

Infection

Blasticidin A ((+)-Blasticidin A) is a tetraamide acid derivative antibiotic produced by Streptomyces griseochromogenes, as well as a selective inhibitor of aflatoxin production. Blasticidin A exhibits antimicrobial activity against yeast. Blasticidin A can be used in research related to aflatoxin contamination (infection by Aspergillus sp.) .
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1
1 Cited Publications
Cat. No.: HY-125747
CAS No.: 18865-48-0
Purity:  98.00%
Synonyms: Actinomycin V (purity≥85%)
Research Areas:  

Infection Cancer

Actinomycin X2 (Actinomycin V), produced by many Streptomyces sp., shows strong inhibition of MRSA with a minimum inhibitory concentration (MIC) value of 0.25 μg/mL. Actinomycin X2 can be used for cancer and bacterial infection .
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1
1 Cited Publications
Cat. No.: HY-130173
CAS No.: 88979-61-7
Purity:  ≥99.0%
Bafilomycin C1 is a macrolide antibiotic isolated from Streptomyces sp. Bafilomycin C1 is a potent, specific and reversible inhibitor of vacuolar-type H +-ATPases (V-ATPases). Bafilomycin C1 inhibits growth of gram-positive bacteria and fungi . Bafilomycin C1 induces cell apoptosis and can be used for the study of hepatocellular carcinoma (HCC) .
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Cat. No.: HY-P2936
CAS No.: 9031-54-3
Target:  

Phospholipase

Research Areas:  

Cardiovascular Disease Infection

Sphingomyelin phosphodiesterase, Streptomyces sp. is a sphingomyelin phosphodiesterase derived from the genus Streptomyces, which cleaves the phosphodiester bond of sphingomyelin. Sphingomyelin phosphodiesterase, Streptomyces sp. catalyzes the hydrolysis of sphingomyelin in micelles, synthetic substrates, erythrocyte ghost membranes and liposomes, as well as the hydrolysis of the substrate HNP. In the presence of Mg 2+ or Mn 2+ , Sphingomyelin phosphodiesterase, Streptomyces sp. induces hemolysis of bovine erythrocytes through the hydrolysis of membrane sphingomyelin .
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Cat. No.: HY-19828
CAS No.: 142861-00-5
Synonyms: GEX1A
Herboxidiene (GEX1A) is a potent phytotoxic polyketide from Streptomyces sp. A7847 with a diverse range of activities, including herbicidal, anti-cholesterol, anti-tumor effects. Herboxidiene inhibits the pre-mRNA splicing process by binding to spliceosome-associated protein (SAP) 155, a subunit of SF3b, in the splicesome .
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Cat. No.: HY-W102907
CAS No.: 4551-72-8
Research Areas:  

Infection

Pyrrole-2-carboxamide (Compound 26) is a secondary metabolite. Pyrrole-2-carboxamide can be produced by two mangrove-derived actinomycetes Streptomyces sp. WHUA03072 and Streptomyces sp. WHUA03267 .
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Cat. No.: HY-N12787
CAS No.: 19912-62-0
Target:  

Others

T-Muurolol is a sesquiterpene and can be isolated from Streptomyces sp. M491 .
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Cat. No.: HY-134090
CAS No.: 51867-94-8
Synonyms: Antibiotic TS 885; NSC 248958
Target:  

Bacterial VSV

Research Areas:  

Infection

9-Methylstreptimidone is a microbial metabolite originally isolated from Streptomyces sp. S-885 that has antifungal and antiviral activities. It is active against several fungi, including S. sake, S. fragilis, R. rubra, T. rubra, and C. albidus (MICs=4-20 μg/mL) and has antiviral activity against poliovirus, vesicular stomatitis virus (VSV), and Newcastle disease virus (NDV) in vitro (MIC=0.02 μg/mL for all). 9-Methylstreptimidone increases survival in mouse models of infection with influenza A2 (H2N2) or C. albicans when administered prior to infection.
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Cat. No.: HY-N8743
CAS No.: 5654-86-4
Synonyms: A 65190; Cyclo-(leucyl-prolyl)
Cyclo(Pro-Leu) (A 65190) is an active metabolite. Cyclo(Pro-Leu) can be isolated from Streptomyces sp. BM8. Cyclo(Pro-Leu) can be used for the research of cancer .
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Cat. No.: HY-118331
CAS No.: 107140-30-7
Synonyms: PD 124895; CL-1957E
Target:  

Antibiotic

Research Areas:  

Infection Cancer

Kazusamycin B is an antibiotic that could be isolated from the fermentation broth of Streptomyces sp. No. 81-484. Kazusamycin B inhibits cell growth and arrests cell cycle at G1 phase. Kazusamycin B can be used in research of cancer .
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Cat. No.: HY-121071
CAS No.: 91432-48-3
Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces sp. JCM9888. Ascamycin has a selective antibacterial activity against Xanthomonas species with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL for Xanthomonas citri, Xanthomonas oryzae and Mycobacterium phlei, respectively .
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Cat. No.: HY-N13017
CAS No.: 701915-56-2
Bhimanone is a bioinactive tetralone, which can be isolated from Streptomyces sp. .
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Cat. No.: HY-N14403
CAS No.: 30954-70-2
Target:  

Cathepsin

6-Hydroxytetrangulol is a CPP32 protease inducer found in Streptomyces sp .
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Cat. No.: HY-131054
CAS No.: 35906-51-5
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Cinerubin B, a glycosylated anthracycline antibiotic, is an anticancer agent from Streptomyces sp. SPB74 .
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Cat. No.: HY-106338
CAS No.: 200625-47-4
Polyketomycin is a tetracyclic quinone glycoside antibiotic isolated from Streptomyces sp. or Streptomyces diastatochromogenes. Polyketomycin inhibits growth of Gram-positive bacteria, and its MIC values is less than 0.2 µg/mL. Polyketomycin has antibacterial, anticancer, antimalarial activities .
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Cat. No.: HY-129558
CAS No.: 151271-53-3
Target:  

HCV

Research Areas:  

Infection Cancer

UK-1 is a cytotoxic metabolite from Streptomyces sp. 517-02 and exerts a wide spectrum of potent anticancer activities . UK-1 also inhibits HCV replication .
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Cat. No.: HY-125637
CAS No.: 33538-72-6
Synonyms: Aabomycin A2
Research Areas:  

Infection

Venturicidin B (Aabomycin A2) is a macrolide antibiotic isolated from Streptomyces sp., used as an antifungal agent, a potent inhibitor of the mitochondrial F0-ATP synthase complex .
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Cat. No.: HY-121452
CAS No.: 314245-65-3
Migrastatin is a typical Fascin1 inhibitor. Migrastatin is isolated from a cultured broth of Streptomyces sp. MK929-43F1. Migrastatin inhibits tumor cell migration .
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Cat. No.: HY-156047
CAS No.: 143452-11-3
Oasomycin B, a member of the desertomycin family, is a polyketide. Oasomycin B can be isolated from Streptomyces sp. Oasomycin B, lacking the positively charged amino moiety, has no significant antibacterial activity and fails to induce Orsellinic acid (HY-N3126) production in A. nidulans .
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