151271-53-3
151271-53-3
Chemical Structure
UK-1
- CAS No.: 151271-53-3
- Formula:C22H14N2O5
- Molecular Weight:386.36
IUPAC Name: methyl 2'-(2-hydroxyphenyl)-[2,4'-bibenzo[d]oxazole]-4-carboxylate
InChIKey: NGKIDJMAXLRJRL-UHFFFAOYSA-N
SMILES: O=C(C1=C2N=C(C3=C4N=C(C5=CC=CC=C5O)OC4=CC=C3)OC2=CC=C1)OC
Biological Activity: UK-1 is a cytotoxic metabolite from Streptomyces sp. 517-02 and exerts a wide spectrum of potent anticancer activities[1]. UK-1 also inhibits HCV replication[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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UK-1 | 95.0% | UK-1 is a cytotoxic metabolite from Streptomyces sp. 517-02 and exerts a wide spectrum of potent anticancer activities. UK-1 also inhibits HCV replication. | ||||||||||||||||||||
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References
- [1]. Ueki M, et al. UK-1, a novel cytotoxic metabolite from Streptomyces sp. 517-02. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties. J Antibiot (Tokyo). 1993 Jul;46(7):1089-94. [Content Brief]
- [2]. Ward DN, et al. UK-1 and structural analogs are potent inhibitors of hepatitis C virus replication. Bioorg Med Chem Lett. 2014 Jan 15;24(2):609-12. [Content Brief]
Keywords
